Versican regulating viscoelasticity drives pleural fibrosis via mechanotransductive signaling.

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Title: Versican regulating viscoelasticity drives pleural fibrosis via mechanotransductive signaling.
Authors: Jia ZH; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., He XL; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Cui XL; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Li Q; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Cheng PP; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zhao LQ; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Ye SY; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Hu SH; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Lian CY; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zhang HD; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Liang LM; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Song LJ; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Yu F; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Xiong L; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Xiang F; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Wang X; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Wang M; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China., Dai X; Department of Thoracic Surgery, Wuhan Pulmonary Hospital, Wuhan, China., Ye H; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Ma WL; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.
Source: JCI insight [JCI Insight] 2026 Apr 23; Vol. 11 (12). Date of Electronic Publication: 2026 Apr 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: Versican regulating viscoelasticity drives pleural fibrosis via mechanotransductive signaling.
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  Data: <searchLink fieldCode="AU" term="%22Jia+ZH%22">Jia ZH</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22He+XL%22">He XL</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Cui+XL%22">Cui XL</searchLink>; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Cheng+PP%22">Cheng PP</searchLink>; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zhao+LQ%22">Zhao LQ</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Ye+SY%22">Ye SY</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Hu+SH%22">Hu SH</searchLink>; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Lian+CY%22">Lian CY</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zhang+HD%22">Zhang HD</searchLink>; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liang+LM%22">Liang LM</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Song+LJ%22">Song LJ</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Yu+F%22">Yu F</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Xiong+L%22">Xiong L</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Xiang+F%22">Xiang F</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Dai+X%22">Dai X</searchLink>; Department of Thoracic Surgery, Wuhan Pulmonary Hospital, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Ye+H%22">Ye H</searchLink>; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.; Department of Pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Ma+WL%22">Ma WL</searchLink>; Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Key Laboratory of Respiratory Diseases of National Health Commission of China, Wuhan, China.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2026 Apr 23; Vol. 11 (12). <i>Date of Electronic Publication: </i>2026 Apr 23 (<i>Print Publication: </i>2026).
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