Blood parameters and whole-blood transcriptomics associated with immune-related adverse events in metastatic renal cell carcinoma during nivolumab plus ipilimumab.
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| Title: | Blood parameters and whole-blood transcriptomics associated with immune-related adverse events in metastatic renal cell carcinoma during nivolumab plus ipilimumab. |
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| Authors: | Kinase S; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Nagumo Y; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Isoda B; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Sakurai H; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Takahashi R; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Suzuki S; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Yamaguchi A; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Yanagihashi R; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Tanuma K; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Nitta S; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Shiga M; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. mshiga@md.tsukuba.ac.jp., Kojo K; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Tsukuba Clinical Research & Development Organization (T-CReDO), University of Tsukuba, Tsukuba, Ibaraki, 305-8576, Japan., Ikeda A; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Kawahara T; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Hoshi A; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Kandori S; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Mathis BJ; Department of Cardiovascular Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan., Nishiyama H; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Center for Cyber Medicine Research, University of Tsukuba, Ibaraki, Japan. |
| Source: | Scientific reports [Sci Rep] 2026 Apr 23; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42026114 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Blood parameters and whole-blood transcriptomics associated with immune-related adverse events in metastatic renal cell carcinoma during nivolumab plus ipilimumab. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kinase+S%22">Kinase S</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Nagumo+Y%22">Nagumo Y</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Isoda+B%22">Isoda B</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Sakurai+H%22">Sakurai H</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+R%22">Takahashi R</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+S%22">Suzuki S</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Yamaguchi+A%22">Yamaguchi A</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Yanagihashi+R%22">Yanagihashi R</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Tanuma+K%22">Tanuma K</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Nitta+S%22">Nitta S</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Shiga+M%22">Shiga M</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. mshiga@md.tsukuba.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kojo+K%22">Kojo K</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Tsukuba Clinical Research & Development Organization (T-CReDO), University of Tsukuba, Tsukuba, Ibaraki, 305-8576, Japan.<br /><searchLink fieldCode="AU" term="%22Ikeda+A%22">Ikeda A</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Kawahara+T%22">Kawahara T</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Hoshi+A%22">Hoshi A</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Kandori+S%22">Kandori S</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Mathis+BJ%22">Mathis BJ</searchLink>; Department of Cardiovascular Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.<br /><searchLink fieldCode="AU" term="%22Nishiyama+H%22">Nishiyama H</searchLink>; Department of Urology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.; Center for Cyber Medicine Research, University of Tsukuba, Ibaraki, Japan. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Apr 23; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Apr 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42026114 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-026-46960-6 Languages: – Code: eng Text: English Titles: – TitleFull: Blood parameters and whole-blood transcriptomics associated with immune-related adverse events in metastatic renal cell carcinoma during nivolumab plus ipilimumab. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kinase S – PersonEntity: Name: NameFull: Nagumo Y – PersonEntity: Name: NameFull: Isoda B – PersonEntity: Name: NameFull: Sakurai H – PersonEntity: Name: NameFull: Takahashi R – PersonEntity: Name: NameFull: Suzuki S – PersonEntity: Name: NameFull: Yamaguchi A – PersonEntity: Name: NameFull: Yanagihashi R – PersonEntity: Name: NameFull: Tanuma K – PersonEntity: Name: NameFull: Nitta S – PersonEntity: Name: NameFull: Shiga M – PersonEntity: Name: NameFull: Kojo K – PersonEntity: Name: NameFull: Ikeda A – PersonEntity: Name: NameFull: Kawahara T – PersonEntity: Name: NameFull: Hoshi A – PersonEntity: Name: NameFull: Kandori S – PersonEntity: Name: NameFull: Mathis BJ – PersonEntity: Name: NameFull: Nishiyama H IsPartOfRelationships: – BibEntity: Dates: – D: 23 M: 04 Text: 2026 Apr 23 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2045-2322 Numbering: – Type: volume Value: 16 – Type: issue Value: 1 Titles: – TitleFull: Scientific reports Type: main |
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