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2,5-Dimethylcelecoxib inhibits lung fibrosis in a mouse model of bleomycin-induced pulmonary fibrosis.

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Title: 2,5-Dimethylcelecoxib inhibits lung fibrosis in a mouse model of bleomycin-induced pulmonary fibrosis.
Authors: Morimoto T; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Ishikane S; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan. Electronic address: ishikane@med.uoeh-u.ac.jp., Arioka M; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Hashimoto K; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Igawa K; Department of Chemistry, Faculty of Advanced Science and Technology, Kumamoto University, Kumamoto, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Higashi Y; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Tomonaga T; Department of Occupational Pneumology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Nishida C; Department of Environmental Health Engineering, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Yatera K; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan., Takahashi-Yanaga F; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.
Source: Respiratory investigation [Respir Investig] 2026 May; Vol. 64 (3), pp. 101429. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101581124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5353 (Electronic) Linking ISSN: 22125345 NLM ISO Abbreviation: Respir Investig Subsets: MEDLINE
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  Data: 2,5-Dimethylcelecoxib inhibits lung fibrosis in a mouse model of bleomycin-induced pulmonary fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Morimoto+T%22">Morimoto T</searchLink>; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Ishikane+S%22">Ishikane S</searchLink>; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan. Electronic address: ishikane@med.uoeh-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Arioka+M%22">Arioka M</searchLink>; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Hashimoto+K%22">Hashimoto K</searchLink>; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Igawa+K%22">Igawa K</searchLink>; Department of Chemistry, Faculty of Advanced Science and Technology, Kumamoto University, Kumamoto, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Higashi+Y%22">Higashi Y</searchLink>; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Tomonaga+T%22">Tomonaga T</searchLink>; Department of Occupational Pneumology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Nishida+C%22">Nishida C</searchLink>; Department of Environmental Health Engineering, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Yatera+K%22">Yatera K</searchLink>; Department of Respiratory Medicine, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi-Yanaga+F%22">Takahashi-Yanaga F</searchLink>; Department of Pharmacology, School of Medicine, University of Occupational and Environmental Health, Japan. 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, Fukuoka, 807-8555, Japan.
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              Text: 2026 May
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