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Cancer IDO1-Mediated Tryptophan-Kynurenine Metabolic Reprogramming to Drive Skeletal Muscle Atrophy and Cachexia Acceleration.

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Title: Cancer IDO1-Mediated Tryptophan-Kynurenine Metabolic Reprogramming to Drive Skeletal Muscle Atrophy and Cachexia Acceleration.
Authors: Han L; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China., Jing L; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhu X; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China., Li C; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai University of Traditional Chinese Medicine, Shanghai, China., Bai L; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; School of Biological and Biomedical Engineering, Donghua University, Shanghai, China., Fang Y; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; School of Biological and Biomedical Engineering, Donghua University, Shanghai, China., Zhou Y; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China., Bai D; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China., Lu J; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China., Han Y; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China., Guo C; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai University of Traditional Chinese Medicine, Shanghai, China., Zhou S; Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China., Yang Q; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; School of Biological and Biomedical Engineering, Donghua University, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China.
Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2026 Jun; Vol. 17 (3), pp. e70295.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cancer IDO1-Mediated Tryptophan-Kynurenine Metabolic Reprogramming to Drive Skeletal Muscle Atrophy and Cachexia Acceleration.
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  Data: <searchLink fieldCode="AU" term="%22Han+L%22">Han L</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Jing+L%22">Jing L</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai University of Traditional Chinese Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Bai+L%22">Bai L</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; School of Biological and Biomedical Engineering, Donghua University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Fang+Y%22">Fang Y</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; School of Biological and Biomedical Engineering, Donghua University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Bai+D%22">Bai D</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Guo+C%22">Guo C</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai University of Traditional Chinese Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Department of Pharmacy, Shanghai Sixth People's Hospital Affiliated Shanghai Jiao Tong University School of Medicine, Shanghai, China.; School of Biological and Biomedical Engineering, Donghua University, Shanghai, China.; College of Food Science, Shanghai Ocean University, Shanghai, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons+Ltd+on+behalf+of+Society+on+Sarcopenia%2C+Cachexia+and+Wasting+Disorders%22">John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101552883 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2190-6009 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221905991%22">21905991 </searchLink><i>NLM ISO Abbreviation: </i>J Cachexia Sarcopenia Muscle <i>Subsets: </i>MEDLINE
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        Value: 10.1002/jcsm.70295
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            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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