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Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age-Related Macular Degeneration.

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Title: Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age-Related Macular Degeneration.
Authors: Molins B; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain., Nabaes Jodar MS; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain., de Oliveira E; Proteomics Laboratory, Biomolecular Analysis Unit. Scientifical and Technological Centers, University of Barcelona, Barcelona, Spain., Estanyol JM; Proteomics Laboratory, Biomolecular Analysis Unit. Scientifical and Technological Centers, University of Barcelona, Barcelona, Spain., Peña E; Research Institute Sant Pau (IR SANT PAU), CIBERCV, Barcelona, Barcelona, Spain., Bezunartea J; Retinal Pathologies and New Therapies Group, Experimental Ophthalmology Laboratory, Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research, IdiSNA, Pamplona, Spain., Hernández M; Retinal Pathologies and New Therapies Group, Experimental Ophthalmology Laboratory, Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research, IdiSNA, Pamplona, Spain., Figueras-Roca M; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic, Barcelona, Barcelona, Spain., Adan A; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic, Barcelona, Barcelona, Spain.
Source: Aging cell [Aging Cell] 2026 May; Vol. 25 (5), pp. e70501.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Decellularized Aged Bruch's Membrane Confers Unique Biochemical Cues to Retinal Pigment Epithelium for In Vitro Modeling of Age-Related Macular Degeneration.
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  Data: <searchLink fieldCode="AU" term="%22Molins+B%22">Molins B</searchLink>; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Nabaes+Jodar+MS%22">Nabaes Jodar MS</searchLink>; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+E%22">de Oliveira E</searchLink>; Proteomics Laboratory, Biomolecular Analysis Unit. Scientifical and Technological Centers, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Estanyol+JM%22">Estanyol JM</searchLink>; Proteomics Laboratory, Biomolecular Analysis Unit. Scientifical and Technological Centers, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Peña+E%22">Peña E</searchLink>; Research Institute Sant Pau (IR SANT PAU), CIBERCV, Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bezunartea+J%22">Bezunartea J</searchLink>; Retinal Pathologies and New Therapies Group, Experimental Ophthalmology Laboratory, Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research, IdiSNA, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Hernández+M%22">Hernández M</searchLink>; Retinal Pathologies and New Therapies Group, Experimental Ophthalmology Laboratory, Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain.; Navarra Institute for Health Research, IdiSNA, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Figueras-Roca+M%22">Figueras-Roca M</searchLink>; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic, Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Adan+A%22">Adan A</searchLink>; Group of Ocular Inflammation: Clinical and Experimental Studies, Institut D'investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic, Barcelona, Barcelona, Spain.
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            – D: 01
              M: 05
              Text: 2026 May
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