Neoadjuvant/adjuvant relugolix and enzalutamide for the treatment of high-risk locally advanced prostate cancer: study protocol of the RENAPCA phase Ib trial.

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Title: Neoadjuvant/adjuvant relugolix and enzalutamide for the treatment of high-risk locally advanced prostate cancer: study protocol of the RENAPCA phase Ib trial.
Authors: Loper M; College of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA matthewloper18@gmail.com., Qadar A; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Vesely SK; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Gunter T; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Ayanambakkam A; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Wen Y; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Cookson M; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Stratton K; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Source: BMJ open [BMJ Open] 2026 Apr 24; Vol. 16 (4), pp. e112623. Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Neoadjuvant/adjuvant relugolix and enzalutamide for the treatment of high-risk locally advanced prostate cancer: study protocol of the RENAPCA phase Ib trial.
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  Data: <searchLink fieldCode="AU" term="%22Loper+M%22">Loper M</searchLink>; College of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA matthewloper18@gmail.com.<br /><searchLink fieldCode="AU" term="%22Qadar+A%22">Qadar A</searchLink>; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Vesely+SK%22">Vesely SK</searchLink>; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Gunter+T%22">Gunter T</searchLink>; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Ayanambakkam+A%22">Ayanambakkam A</searchLink>; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Wen+Y%22">Wen Y</searchLink>; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Cookson+M%22">Cookson M</searchLink>; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.<br /><searchLink fieldCode="AU" term="%22Stratton+K%22">Stratton K</searchLink>; The Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
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  Data: <searchLink fieldCode="JN" term="%22101552874%22">BMJ open</searchLink> [BMJ Open] 2026 Apr 24; Vol. 16 (4), pp. e112623. <i>Date of Electronic Publication: </i>2026 Apr 24.
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        Value: 10.1136/bmjopen-2025-112623
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              Text: 2026 Apr 24
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