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MechanoAge, a machine learning platform to identify individuals susceptible to breast cancer based on mechanical properties of single cells.

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Title: MechanoAge, a machine learning platform to identify individuals susceptible to breast cancer based on mechanical properties of single cells.
Authors: Hinz S; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA. Electronic address: shinz@coh.org., Grøndal SM; Department of Biomedicine & Centre for Cancer Biomarkers, University of Bergen, Bergen, Norway., Miyano M; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA., Lopez JC; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA., Cotner KL; UC Berkeley-UC San Francisco Graduate Program in Bioengineering, University of California, Berkeley, CA, USA., Thomsen T; UC Berkeley-UC San Francisco Graduate Program in Bioengineering, University of California, Berkeley, CA, USA., Chen C; Department of Mechanical Engineering, University of California, Berkeley, CA, USA., Hester EJ; Department of Mechanical Engineering, University of California, Berkeley, CA, USA., Yee LD; Department of Surgery, City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Seewaldt VE; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA., Lorens JB; Department of Biomedicine & Centre for Cancer Biomarkers, University of Bergen, Bergen, Norway., Sohn LL; Department of Mechanical Engineering, University of California, Berkeley, CA, USA., LaBarge MA; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA; Center for Cancer and Aging Research, City of Hope, Duarte, CA, USA. Electronic address: mlabarge@coh.org.
Source: EBioMedicine [EBioMedicine] 2026 May; Vol. 127, pp. 106241. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hinz+S%22">Hinz S</searchLink>; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA. Electronic address: shinz@coh.org.<br /><searchLink fieldCode="AU" term="%22Grøndal+SM%22">Grøndal SM</searchLink>; Department of Biomedicine & Centre for Cancer Biomarkers, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Miyano+M%22">Miyano M</searchLink>; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lopez+JC%22">Lopez JC</searchLink>; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cotner+KL%22">Cotner KL</searchLink>; UC Berkeley-UC San Francisco Graduate Program in Bioengineering, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Thomsen+T%22">Thomsen T</searchLink>; UC Berkeley-UC San Francisco Graduate Program in Bioengineering, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Department of Mechanical Engineering, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hester+EJ%22">Hester EJ</searchLink>; Department of Mechanical Engineering, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yee+LD%22">Yee LD</searchLink>; Department of Surgery, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Seewaldt+VE%22">Seewaldt VE</searchLink>; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lorens+JB%22">Lorens JB</searchLink>; Department of Biomedicine & Centre for Cancer Biomarkers, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Sohn+LL%22">Sohn LL</searchLink>; Department of Mechanical Engineering, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22LaBarge+MA%22">LaBarge MA</searchLink>; Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA, USA; Center for Cancer and Aging Research, City of Hope, Duarte, CA, USA. Electronic address: mlabarge@coh.org.
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  Data: <searchLink fieldCode="JN" term="%22101647039%22">EBioMedicine</searchLink> [EBioMedicine] 2026 May; Vol. 127, pp. 106241. <i>Date of Electronic Publication: </i>2026 Apr 23.
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