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Nucleoporin TPR integrates MAPK signaling with mitogen-induced transcriptional programs.

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Title: Nucleoporin TPR integrates MAPK signaling with mitogen-induced transcriptional programs.
Authors: Liu J; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK., Zheng Y; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK., Xiong Y; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK., Ma R; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK., Lin Z; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK., Lin H; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK., Andújar-Sánchez M; Pathology Department, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas de Gran Canaria, Spain., Bartkova J; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.; Danish Cancer Institute, Danish Cancer Society, Copenhagen, Denmark., Liu J; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.; Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Biomedical and Health Translational Research Center of Zhejiang Province, Haining, China., Foiani M; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milano, Italy., Bartek J; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden. jb@cancer.dk.; Danish Cancer Institute, Danish Cancer Society, Copenhagen, Denmark. jb@cancer.dk., Kosar M; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China. martinkosar@intl.zju.edu.cn.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK. martinkosar@intl.zju.edu.cn.; Biomedical and Health Translational Research Center of Zhejiang Province, Haining, China. martinkosar@intl.zju.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 24; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
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  Data: Nucleoporin TPR integrates MAPK signaling with mitogen-induced transcriptional programs.
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  Data: <searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Xiong+Y%22">Xiong Y</searchLink>; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Ma+R%22">Ma R</searchLink>; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Andújar-Sánchez+M%22">Andújar-Sánchez M</searchLink>; Pathology Department, Complejo Hospitalario Universitario Insular Materno Infantil, Las Palmas de Gran Canaria, Spain.<br /><searchLink fieldCode="AU" term="%22Bartkova+J%22">Bartkova J</searchLink>; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.; Danish Cancer Institute, Danish Cancer Society, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK.; Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China.; Biomedical and Health Translational Research Center of Zhejiang Province, Haining, China.<br /><searchLink fieldCode="AU" term="%22Foiani+M%22">Foiani M</searchLink>; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Bartek+J%22">Bartek J</searchLink>; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden. jb@cancer.dk.; Danish Cancer Institute, Danish Cancer Society, Copenhagen, Denmark. jb@cancer.dk.<br /><searchLink fieldCode="AU" term="%22Kosar+M%22">Kosar M</searchLink>; Department of Burns, the Second Affiliated Hospital of Zhejiang University School of Medicine, and the Centre for Infection, Immunity, and Cancer (IIC) at Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Haining, China. martinkosar@intl.zju.edu.cn.; Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK. martinkosar@intl.zju.edu.cn.; Biomedical and Health Translational Research Center of Zhejiang Province, Haining, China. martinkosar@intl.zju.edu.cn.
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