Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo.
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| Title: | Transcriptomic and phenotypic convergence of neurodevelopmental disorder risk genes in vitro and in vivo. |
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| Authors: | Fernandez Garcia M; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Retallick-Townsley K; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Pruitt A; Interdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA., Davidson EA; Child Study Center, Yale University School of Medicine, New Haven, CT, USA., Balafkan N; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen, Norway., Warrell J; Department of Molecular Biophysics & Biochemistry and Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Huang TC; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Easton, MD, USA., Kibowen A; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Chu Z; Department of Molecular Biophysics & Biochemistry and Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Dai Y; Department of Biostatistics, Yale University School of Public Health, New Haven, CT, USA., Fitzpatrick SE; Interdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA.; Medical Scientist Training Program, Yale School of Medicine, New Haven, CT, USA., Meng R; Department of Molecular Biophysics & Biochemistry and Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Sen A; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Cohen S; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Livoti O; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Khan S; Child Study Center, Yale University School of Medicine, New Haven, CT, USA., Becker C; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Luiz Teles E Silva A; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Hospital Israelita Albert Einstein, São Paulo, Brazil., Liu J; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Dossou G; Child Study Center, Yale University School of Medicine, New Haven, CT, USA., Cheung J; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Liu S; Department of Molecular Biophysics & Biochemistry and Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Ghorbani S; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen, Norway., Deans PJM; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., DeCiucis M; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Easton, MD, USA.; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.; Systems Biology Institute, Yale West Campus, West Haven, CT, USA., Emani P; Department of Molecular Biophysics & Biochemistry and Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Gao H; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Shen H; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Easton, MD, USA.; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.; Systems Biology Institute, Yale West Campus, West Haven, CT, USA., Gerstein M; Department of Molecular Biophysics & Biochemistry and Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA., Wang Z; Department of Biostatistics, Yale University School of Public Health, New Haven, CT, USA.; Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA., Huckins LM; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Interdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA., Hoffman EJ; Child Study Center, Yale University School of Medicine, New Haven, CT, USA. ellen.hoffman@yale.edu.; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, USA. ellen.hoffman@yale.edu.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT, USA. ellen.hoffman@yale.edu., Brennand K; Division of Molecular Psychiatry, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. kristen.brennand@yale.edu.; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. kristen.brennand@yale.edu.; Interdepartmental Neuroscience Program, Yale School of Medicine, New Haven, CT, USA. kristen.brennand@yale.edu.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Easton, MD, USA. kristen.brennand@yale.edu.; Wu Tsai Institute, Yale University School of Medicine, New Haven, CT, USA. kristen.brennand@yale.edu.; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA. kristen.brennand@yale.edu. |
| Source: | Nature neuroscience [Nat Neurosci] 2026 May; Vol. 29 (5), pp. 1079-1094. Date of Electronic Publication: 2026 Apr 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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