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m6A-Mediated epitranscriptional reprogramming drives cardiac fibrosis by suppressing PGC-1α and boosting mitochondrial fission.

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Title: m6A-Mediated epitranscriptional reprogramming drives cardiac fibrosis by suppressing PGC-1α and boosting mitochondrial fission.
Authors: Cao XY; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China., Tu B; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Cao ZR; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Liu F; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China., Yan G; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Dong J; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Huang QW; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Li ZJ; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China., Liu QY; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China., Leng JJ; Department of Anatomy and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College of Chongqing Medical University, Chongqing, 400016, China., Yu WC; Department of Nuclear Medicine, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China. 531765185@qq.com., Bie MJ; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. 513193406@qq.com., Wang XW; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. xiaowenwang@cqmu.edu.cn., Jiang YJ; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China. 18996902974@163.com.; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. 18996902974@163.com.
Source: Journal of translational medicine [J Transl Med] 2026 Apr 24; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: m6A-Mediated epitranscriptional reprogramming drives cardiac fibrosis by suppressing PGC-1α and boosting mitochondrial fission.
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  Data: <searchLink fieldCode="AU" term="%22Cao+XY%22">Cao XY</searchLink>; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China.<br /><searchLink fieldCode="AU" term="%22Tu+B%22">Tu B</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Cao+ZR%22">Cao ZR</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Liu+F%22">Liu F</searchLink>; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China.<br /><searchLink fieldCode="AU" term="%22Yan+G%22">Yan G</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Dong+J%22">Dong J</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Huang+QW%22">Huang QW</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Li+ZJ%22">Li ZJ</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Liu+QY%22">Liu QY</searchLink>; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China.<br /><searchLink fieldCode="AU" term="%22Leng+JJ%22">Leng JJ</searchLink>; Department of Anatomy and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College of Chongqing Medical University, Chongqing, 400016, China.<br /><searchLink fieldCode="AU" term="%22Yu+WC%22">Yu WC</searchLink>; Department of Nuclear Medicine, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China. 531765185@qq.com.<br /><searchLink fieldCode="AU" term="%22Bie+MJ%22">Bie MJ</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. 513193406@qq.com.<br /><searchLink fieldCode="AU" term="%22Wang+XW%22">Wang XW</searchLink>; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. xiaowenwang@cqmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Jiang+YJ%22">Jiang YJ</searchLink>; Department of Cardiothoracic Surgery, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing, 402160, China. 18996902974@163.com.; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China. 18996902974@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Apr 24; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Apr 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 24
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