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Opportunities and challenges related to participant stratification and cohort enrichment in ALS clinical trials.

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Title: Opportunities and challenges related to participant stratification and cohort enrichment in ALS clinical trials.
Authors: Yusuf S; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada., Allen MD; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.; Ottawa Hospital Research Institute, Ottawa, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Ottawa, Ottawa, Canada., Kang H; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada., Phillips DE; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada., Genge A; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.
Source: Amyotrophic lateral sclerosis & frontotemporal degeneration [Amyotroph Lateral Scler Frontotemporal Degener] 2026 Apr 25, pp. 1-10. Date of Electronic Publication: 2026 Apr 25.
Publication Type: Journal Article; Review
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101587185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2167-9223 (Electronic) Linking ISSN: 21678421 NLM ISO Abbreviation: Amyotroph Lateral Scler Frontotemporal Degener Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yusuf+S%22">Yusuf S</searchLink>; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Allen+MD%22">Allen MD</searchLink>; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.; Ottawa Hospital Research Institute, Ottawa, Canada.; Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Ottawa, Ottawa, Canada.<br /><searchLink fieldCode="AU" term="%22Kang+H%22">Kang H</searchLink>; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Phillips+DE%22">Phillips DE</searchLink>; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Genge+A%22">Genge A</searchLink>; Department of Neurology and Neurosurgery, McGill University, Montreal, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101587185%22">Amyotrophic lateral sclerosis & frontotemporal degeneration</searchLink> [Amyotroph Lateral Scler Frontotemporal Degener] 2026 Apr 25, pp. 1-10. <i>Date of Electronic Publication: </i>2026 Apr 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101587185 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2167-9223 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221678421%22">21678421 </searchLink><i>NLM ISO Abbreviation: </i>Amyotroph Lateral Scler Frontotemporal Degener <i>Subsets: </i>MEDLINE
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        Value: 10.1080/21678421.2026.2659128
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      – Code: eng
        Text: English
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      – TitleFull: Opportunities and challenges related to participant stratification and cohort enrichment in ALS clinical trials.
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            – D: 25
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              Text: 2026 Apr 25
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