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Peripheral inflammation is associated with reduced influx of TSPO PET tracers into the brain: insights from a non-invasive mapping methodology.

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Title: Peripheral inflammation is associated with reduced influx of TSPO PET tracers into the brain: insights from a non-invasive mapping methodology.
Authors: Barzon L; Department of Information Engineering, University of Padova, Padova, Italy. Electronic address: leonardo.barzon.1@phd.unipd.it., Maccioni L; Department of Information Engineering, University of Padova, Padova, Italy., Moretto M; Department of Information Engineering, University of Padova, Padova, Italy; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Giacomel A; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Schubert JJ; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Cousins O; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Rosenzweig I; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Mizuno Y; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK; South London and Maudsley NHS Foundation Trust, London, UK; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan., Reis Marques T; Psychiatric Imaging Group, MRC London Institute of Medical Sciences (LMS), Hammersmith Hospital, Imperial College London, London, UK., Harrison NA; Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK., Fryer T; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Bullmore ET; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Mondelli V; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Pariante C; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Howes O; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Turkheimer FE; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK., Veronese M; Department of Information Engineering, University of Padova, Padova, Italy; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK. Electronic address: mattia.veronese@unipd.it.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Aug; Vol. 136, pp. 106779. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
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  Data: Peripheral inflammation is associated with reduced influx of TSPO PET tracers into the brain: insights from a non-invasive mapping methodology.
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  Data: <searchLink fieldCode="AU" term="%22Barzon+L%22">Barzon L</searchLink>; Department of Information Engineering, University of Padova, Padova, Italy. Electronic address: leonardo.barzon.1@phd.unipd.it.<br /><searchLink fieldCode="AU" term="%22Maccioni+L%22">Maccioni L</searchLink>; Department of Information Engineering, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Moretto+M%22">Moretto M</searchLink>; Department of Information Engineering, University of Padova, Padova, Italy; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Giacomel+A%22">Giacomel A</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Schubert+JJ%22">Schubert JJ</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Cousins+O%22">Cousins O</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rosenzweig+I%22">Rosenzweig I</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mizuno+Y%22">Mizuno Y</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK; South London and Maudsley NHS Foundation Trust, London, UK; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Reis+Marques+T%22">Reis Marques T</searchLink>; Psychiatric Imaging Group, MRC London Institute of Medical Sciences (LMS), Hammersmith Hospital, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Harrison+NA%22">Harrison NA</searchLink>; Cardiff University Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Fryer+T%22">Fryer T</searchLink>; Department of Clinical Neurosciences, School of Clinical Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bullmore+ET%22">Bullmore ET</searchLink>; Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Mondelli+V%22">Mondelli V</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Pariante+C%22">Pariante C</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Howes+O%22">Howes O</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Turkheimer+FE%22">Turkheimer FE</searchLink>; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Veronese+M%22">Veronese M</searchLink>; Department of Information Engineering, University of Padova, Padova, Italy; Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK. Electronic address: mattia.veronese@unipd.it.
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