Genetic drivers of progression in Alzheimer's disease are distinct from disease risk.

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Bibliographic Details
Title: Genetic drivers of progression in Alzheimer's disease are distinct from disease risk.
Authors: Cohen CE; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Wellcome Sanger Institute, Cambridge, UK., Fernandez S; Centre for Precision Health, Edith Cowan University, Joondalup, WA, Australia.; Collaborative Genomics and Translation Group, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia., Yaman U; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, University College London, London, UK., Ehyaei AR; Max-Planck-Institute for Intelligent Systems, Tubingen, Germany., Kodosaki E; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, University College London, London, UK., Askarova A; UK Dementia Research Institute, Imperial College London, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Porter T; Centre for Precision Health, Edith Cowan University, Joondalup, WA, Australia.; Collaborative Genomics and Translation Group, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia., O'Brien E; Centre for Precision Health, Edith Cowan University, Joondalup, WA, Australia.; Collaborative Genomics and Translation Group, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia., Maruff P; Florey Department of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.; CogState Ltd, Melbourne, Australia., Nott A; UK Dementia Research Institute, Imperial College London, London, UK.; Department of Brain Sciences, Imperial College London, London, UK., Hardy JA; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, University College London, London, UK.; Reta Lila Weston Institute of Neurological Studies, London, UK., Laws SM; Centre for Precision Health, Edith Cowan University, Joondalup, WA, Australia.; Collaborative Genomics and Translation Group, School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia., A Salih D; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK.; Dementia Research Institute, University College London, London, UK., Shoai M; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK. m.shoai@ucl.ac.uk.; Dementia Research Institute, University College London, London, UK. m.shoai@ucl.ac.uk.
Corporate Authors: Australian Imaging Biomarkers and Lifestyle Study, Alzheimer’s Disease Neuroimaging Initiative
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2026 Apr 25; Vol. 18 (1). Date of Electronic Publication: 2026 Apr 25.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1758-9193
DOI:10.1186/s13195-026-02036-1