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On-site loading of powder-attached microneedles enables quantitative and reproducible intradermal vaccine delivery.

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Title: On-site loading of powder-attached microneedles enables quantitative and reproducible intradermal vaccine delivery.
Authors: Kim S; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea., Kim H; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea., Kwon MJ; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea., Ryu M; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea., Kim JS; R&D Centre, QuadMedicine Inc., Sagimakgol-ro, 45beon-gil, Jungwon-gu, Seongnam-si, Gyeonggi-do 13209, the Republic of Korea., Baek SK; R&D Centre, QuadMedicine Inc., Sagimakgol-ro, 45beon-gil, Jungwon-gu, Seongnam-si, Gyeonggi-do 13209, the Republic of Korea., Kim C; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea., Lee JM; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea., Kwak K; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea. Electronic address: KIHYUCKKWAK@yuhs.ac., Park JH; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea. Electronic address: pa90201@gachon.ac.kr.
Source: International journal of pharmaceutics [Int J Pharm] 2026 Jun 05; Vol. 698, pp. 126906. Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
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  Data: On-site loading of powder-attached microneedles enables quantitative and reproducible intradermal vaccine delivery.
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  Data: <searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+MJ%22">Kwon MJ</searchLink>; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryu+M%22">Ryu M</searchLink>; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JS%22">Kim JS</searchLink>; R&D Centre, QuadMedicine Inc., Sagimakgol-ro, 45beon-gil, Jungwon-gu, Seongnam-si, Gyeonggi-do 13209, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Baek+SK%22">Baek SK</searchLink>; R&D Centre, QuadMedicine Inc., Sagimakgol-ro, 45beon-gil, Jungwon-gu, Seongnam-si, Gyeonggi-do 13209, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+C%22">Kim C</searchLink>; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JM%22">Lee JM</searchLink>; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwak+K%22">Kwak K</searchLink>; Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, the Republic of Korea. Electronic address: KIHYUCKKWAK@yuhs.ac.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; Department of BioNano Technology, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si, Gyeonggi-do 13120, the Republic of Korea. Electronic address: pa90201@gachon.ac.kr.
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              Text: 2026 Jun 05
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