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Bradykinin modulates endothelin-1-enhanced and monocrotaline-induced pulmonary arterial hypertension-associated arrhythmogenesis in rabbit right ventricular outflow tract via a nitric oxide-dependent pathway.

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Title: Bradykinin modulates endothelin-1-enhanced and monocrotaline-induced pulmonary arterial hypertension-associated arrhythmogenesis in rabbit right ventricular outflow tract via a nitric oxide-dependent pathway.
Authors: Lu YY; Division of Cardiology, Sijhih Cathay General Hospital, New Taipei City, Taiwan; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan., Lin FJ; Department of Biomedical Engineering, College of Oral Medicine, National Defense Medical University, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Chen YC; Department of Biomedical Engineering, College of Oral Medicine, National Defense Medical University, Taipei, Taiwan., Chin CG; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Cardiovascular Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan., Chan CS; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Cardiology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan., Higa S; Cardiac Electrophysiology and Pacing Laboratory, Division of Cardiovascular Medicine, Makiminato Central Hospital, Okinawa, Japan., Chen YJ; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Cardiovascular Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Cardiovascular Research Center, Wan-Fang Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address: yjchen@tmu.edu.tw.
Source: European journal of pharmacology [Eur J Pharmacol] 2026 May 15; Vol. 1024, pp. 178896. Date of Electronic Publication: 2026 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bradykinin modulates endothelin-1-enhanced and monocrotaline-induced pulmonary arterial hypertension-associated arrhythmogenesis in rabbit right ventricular outflow tract via a nitric oxide-dependent pathway.
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  Data: <searchLink fieldCode="AU" term="%22Lu+YY%22">Lu YY</searchLink>; Division of Cardiology, Sijhih Cathay General Hospital, New Taipei City, Taiwan; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+FJ%22">Lin FJ</searchLink>; Department of Biomedical Engineering, College of Oral Medicine, National Defense Medical University, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YC%22">Chen YC</searchLink>; Department of Biomedical Engineering, College of Oral Medicine, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chin+CG%22">Chin CG</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Cardiovascular Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chan+CS%22">Chan CS</searchLink>; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Cardiology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Higa+S%22">Higa S</searchLink>; Cardiac Electrophysiology and Pacing Laboratory, Division of Cardiovascular Medicine, Makiminato Central Hospital, Okinawa, Japan.<br /><searchLink fieldCode="AU" term="%22Chen+YJ%22">Chen YJ</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Cardiovascular Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Cardiovascular Research Center, Wan-Fang Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address: yjchen@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%221254354%22">European journal of pharmacology</searchLink> [Eur J Pharmacol] 2026 May 15; Vol. 1024, pp. 178896. <i>Date of Electronic Publication: </i>2026 Apr 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>1254354 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0712 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200142999%22">00142999 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Pharmacol <i>Subsets: </i>MEDLINE
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              Text: 2026 May 15
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