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Association between baseline circulating FGF21 levels and depressive symptoms at follow up in older adults: evidence from the FRASNET cohort.

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Title: Association between baseline circulating FGF21 levels and depressive symptoms at follow up in older adults: evidence from the FRASNET cohort.
Authors: Damanti S; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Sciorati C; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy., Avola A; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy., De Lorenzo R; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy., Brioni E; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy., Farina F; Vita-Salute San Raffaele University, Milan, Italy., Festorazzi C; Vita-Salute San Raffaele University, Milan, Italy., Laffranchi M; Vita-Salute San Raffaele University, Milan, Italy., Mallus M; Vita-Salute San Raffaele University, Milan, Italy., Messina M; Vita-Salute San Raffaele University, Milan, Italy., Pata G; Vita-Salute San Raffaele University, Milan, Italy., Ruggiero M; Vita-Salute San Raffaele University, Milan, Italy., Senini E; Vita-Salute San Raffaele University, Milan, Italy., Santoro S; Vita-Salute San Raffaele University, Milan, Italy., Zagato L; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Citterio L; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Simonini M; Nephrology and Dialysis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Manfredi AA; Vita-Salute San Raffaele University, Milan, Italy., Manunta P; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Nephrology and Dialysis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Lanzani C; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Nephrology and Dialysis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Rovere-Querini P; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
Source: Frontiers in psychiatry [Front Psychiatry] 2026 Apr 10; Vol. 17, pp. 1726636. Date of Electronic Publication: 2026 Apr 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101545006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-0640 (Print) Linking ISSN: 16640640 NLM ISO Abbreviation: Front Psychiatry Subsets: PubMed not MEDLINE
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  Data: Association between baseline circulating FGF21 levels and depressive symptoms at follow up in older adults: evidence from the FRASNET cohort.
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  Data: <searchLink fieldCode="AU" term="%22Damanti+S%22">Damanti S</searchLink>; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sciorati+C%22">Sciorati C</searchLink>; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Avola+A%22">Avola A</searchLink>; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22De+Lorenzo+R%22">De Lorenzo R</searchLink>; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Brioni+E%22">Brioni E</searchLink>; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Farina+F%22">Farina F</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Festorazzi+C%22">Festorazzi C</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Laffranchi+M%22">Laffranchi M</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mallus+M%22">Mallus M</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Messina+M%22">Messina M</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pata+G%22">Pata G</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ruggiero+M%22">Ruggiero M</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Senini+E%22">Senini E</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Santoro+S%22">Santoro S</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zagato+L%22">Zagato L</searchLink>; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Citterio+L%22">Citterio L</searchLink>; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Simonini+M%22">Simonini M</searchLink>; Nephrology and Dialysis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Manfredi+AA%22">Manfredi AA</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Manunta+P%22">Manunta P</searchLink>; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Nephrology and Dialysis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Lanzani+C%22">Lanzani C</searchLink>; Genomics of Renal Disease and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Nephrology and Dialysis Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rovere-Querini+P%22">Rovere-Querini P</searchLink>; Innate Immunity and Tissue Remodelling Unit, IRCCS Ospedale San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
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