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Not so cold after all: tumor infiltrating CD8+ T cells in EBV-positive Burkitt lymphoma are quiescent, not exhausted.

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Title: Not so cold after all: tumor infiltrating CD8+ T cells in EBV-positive Burkitt lymphoma are quiescent, not exhausted.
Authors: Forconi CS; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Oduor CI; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Saikumar PL; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Racenet ZJ; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Fujimori G; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., M'Bana V; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Matta A; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Melo J; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Läderach F; Department of Viral Immunobiology, Institute of Experimental Immunology, University of Zürich, Switzerland., Maina TK; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Otieno JA; Jaramogi Oginga Odinga Teaching and Referral Hospital, Kisumu, Kenya., Dan C; Moi Teaching and Referral Hospital, Eldoret, Kenya., Kibor K; Moi Teaching and Referral Hospital, Eldoret, Kenya., Njuguna F; Moi Teaching and Referral Hospital, Eldoret, Kenya., Vik T; Department of Pediatric Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA., Kinyua AW; Center for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya., Münz C; Department of Viral Immunobiology, Institute of Experimental Immunology, University of Zürich, Switzerland., Bailey JA; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Moormann AM; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 19. Date of Electronic Publication: 2026 Apr 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Not so cold after all: tumor infiltrating CD8+ T cells in EBV-positive Burkitt lymphoma are quiescent, not exhausted.
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  Data: <searchLink fieldCode="AU" term="%22Forconi+CS%22">Forconi CS</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Oduor+CI%22">Oduor CI</searchLink>; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Saikumar+PL%22">Saikumar PL</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Racenet+ZJ%22">Racenet ZJ</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fujimori+G%22">Fujimori G</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22M'Bana+V%22">M'Bana V</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Matta+A%22">Matta A</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Melo+J%22">Melo J</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Läderach+F%22">Läderach F</searchLink>; Department of Viral Immunobiology, Institute of Experimental Immunology, University of Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maina+TK%22">Maina TK</searchLink>; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Otieno+JA%22">Otieno JA</searchLink>; Jaramogi Oginga Odinga Teaching and Referral Hospital, Kisumu, Kenya.<br /><searchLink fieldCode="AU" term="%22Dan+C%22">Dan C</searchLink>; Moi Teaching and Referral Hospital, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Kibor+K%22">Kibor K</searchLink>; Moi Teaching and Referral Hospital, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Njuguna+F%22">Njuguna F</searchLink>; Moi Teaching and Referral Hospital, Eldoret, Kenya.<br /><searchLink fieldCode="AU" term="%22Vik+T%22">Vik T</searchLink>; Department of Pediatric Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Kinyua+AW%22">Kinyua AW</searchLink>; Center for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.<br /><searchLink fieldCode="AU" term="%22Münz+C%22">Münz C</searchLink>; Department of Viral Immunobiology, Institute of Experimental Immunology, University of Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bailey+JA%22">Bailey JA</searchLink>; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Moormann+AM%22">Moormann AM</searchLink>; Department of Medicine, Division of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
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