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Atomic structures of medin and Aβ fibrils reveal polymorphic remodeling in mixed amyloid systems.

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Title: Atomic structures of medin and Aβ fibrils reveal polymorphic remodeling in mixed amyloid systems.
Authors: Pradhan B; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Kumar ST; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; National Centre for Cell Science, Pune, India., Wagner J; Biomedical Center (BMC), Biochemistry, Faculty of Medicine, LMU Munich, Munich, Germany., Gallardo R; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Orlando G; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; Laboratory of Pathogens and Host Immunity, University of Montpellier, CNRS and INSERM, Montpellier, France., De Vleeschouwer M; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Zorzini V; VIB Center for Neuroscience Leuven, Biophysics Technology Unit, Herestraat 49, Leuven, Belgium., Madine J; Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom., Louros N; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; Center for Alzheimer's and Neurodegenerative Diseases, UT Southwestern Medical centre, Dallas, Texas, USA., Neher JJ; Biomedical Center (BMC), Biochemistry, Faculty of Medicine, LMU Munich, Munich, Germany.; Neuroimmunology and Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Rousseau F; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium. frederic.rousseau@kuleuven.be.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium. frederic.rousseau@kuleuven.be., Schymkowitz J; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium. joost.schymkowitz@kuleuven.be.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium. joost.schymkowitz@kuleuven.be.
Source: Nature communications [Nat Commun] 2026 Apr 28; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Atomic structures of medin and Aβ fibrils reveal polymorphic remodeling in mixed amyloid systems.
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  Data: <searchLink fieldCode="AU" term="%22Pradhan+B%22">Pradhan B</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Kumar+ST%22">Kumar ST</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; National Centre for Cell Science, Pune, India.<br /><searchLink fieldCode="AU" term="%22Wagner+J%22">Wagner J</searchLink>; Biomedical Center (BMC), Biochemistry, Faculty of Medicine, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gallardo+R%22">Gallardo R</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Orlando+G%22">Orlando G</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; Laboratory of Pathogens and Host Immunity, University of Montpellier, CNRS and INSERM, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22De+Vleeschouwer+M%22">De Vleeschouwer M</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Zorzini+V%22">Zorzini V</searchLink>; VIB Center for Neuroscience Leuven, Biophysics Technology Unit, Herestraat 49, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Madine+J%22">Madine J</searchLink>; Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Louros+N%22">Louros N</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.; Center for Alzheimer's and Neurodegenerative Diseases, UT Southwestern Medical centre, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Neher+JJ%22">Neher JJ</searchLink>; Biomedical Center (BMC), Biochemistry, Faculty of Medicine, LMU Munich, Munich, Germany.; Neuroimmunology and Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.; Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Rousseau+F%22">Rousseau F</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium. frederic.rousseau@kuleuven.be.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium. frederic.rousseau@kuleuven.be.<br /><searchLink fieldCode="AU" term="%22Schymkowitz+J%22">Schymkowitz J</searchLink>; Switch Laboratory, VIB Center for Neuroscience Leuven, Leuven, Belgium. joost.schymkowitz@kuleuven.be.; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium. joost.schymkowitz@kuleuven.be.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Apr 28; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 28.
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              Text: 2026 Apr 28
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