High Serum IgE is Associated with Risk of Severe Exacerbations Among Non-Eosinophilic Bronchiectasis.

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Title: High Serum IgE is Associated with Risk of Severe Exacerbations Among Non-Eosinophilic Bronchiectasis.
Authors: Kao TW; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan., Wang YH; Medical Research Center, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan., Chang CL; Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, HsinChu, Taiwan., Sheu CC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Wang PH; Division of Thoracic Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan., Hsieh MH; Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Hsu WH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; Critical Medical Center, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan., Chen MT; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan., Ou WF; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan., Wei YF; School of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung, Taiwan.; Department of Internal Medicine, E-Da Cancer Hospital, I-Shou University, Kaohsiung, Taiwan., Yang TM; Division of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan., Lan CC; Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan., Wang CY; Department of Internal Medicine, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, No. 362, Zhongzheng Road, Xindian District, New Taipei City, 23148, Taiwan. cywang@mospital.com., Lin CB; Division of Pulmonary Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; School of Medicine, Tzu-Chi University, Hualien, Taiwan., Lin MS; Division of Pulmonary Medicine, Department of Internal Medicine, Chia-Yi Chrisitian Hospital, Chiayi, Taiwan., Wang YT; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Lin CH; Department of Internal Medicine, Division of Chest Medicine, Changhua Christian Hospital, Changhua, Taiwan.; Institute of Genomics and Bioinformatics, National Chung Hsing University, Taichung, Taiwan.; Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan., Liu SF; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Cheng MH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan., Chen YF; Department of Internal Medicine, Yunlin Branch, National Taiwan University Hospital, Douliu, Taiwan.; Thoracic Medicine Center, Yunlin Branch, National Taiwan University Hospital, Douliu, Taiwan., Cheng WC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan., Peng CK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.; Department of Medicine, Hualien Armed Forces General Hospital, Hualien, Taiwan., Chan MC; Department of Critical Care Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Post Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan., Chen CY; Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan., Jao LY; School of Medicine, Tzu-Chi University, Hualien, Taiwan., Chen CJ; Division of Pulmonary Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Chen SP; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Tsai YH; Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Department of Pulmonary Medicine, Lees Clinic, Pingtung, Taiwan., Cheng SL; Division of Thoracic Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan., Lin HC; Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Respiratory Therapy, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan., Chien JY; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan., Wang HC; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Respiratory Therapy, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; Department of Medicine, National Taiwan University Cancer Center, National Taiwan University College of Medicine, Taipei, Taiwan.
Corporate Authors: Taiwan Bronchiectasis Research Collaboration (TBARC)
Source: Lung [Lung] 2026 Apr 27; Vol. 204 (1). Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7701875 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1750 (Electronic) Linking ISSN: 03412040 NLM ISO Abbreviation: Lung Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High Serum IgE is Associated with Risk of Severe Exacerbations Among Non-Eosinophilic Bronchiectasis.
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  Data: <searchLink fieldCode="AU" term="%22Kao+TW%22">Kao TW</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+YH%22">Wang YH</searchLink>; Medical Research Center, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CL%22">Chang CL</searchLink>; Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, HsinChu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sheu+CC%22">Sheu CC</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+PH%22">Wang PH</searchLink>; Division of Thoracic Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+MH%22">Hsieh MH</searchLink>; Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+WH%22">Hsu WH</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; Critical Medical Center, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+MT%22">Chen MT</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ou+WF%22">Ou WF</searchLink>; Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wei+YF%22">Wei YF</searchLink>; School of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung, Taiwan.; Department of Internal Medicine, E-Da Cancer Hospital, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+TM%22">Yang TM</searchLink>; Division of Pulmonary and Critical Care Medicine, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lan+CC%22">Lan CC</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CY%22">Wang CY</searchLink>; Department of Internal Medicine, Cardinal Tien Hospital and School of Medicine, College of Medicine, Fu Jen Catholic University, No. 362, Zhongzheng Road, Xindian District, New Taipei City, 23148, Taiwan. cywang@mospital.com.<br /><searchLink fieldCode="AU" term="%22Lin+CB%22">Lin CB</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; School of Medicine, Tzu-Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+MS%22">Lin MS</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Chia-Yi Chrisitian Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+YT%22">Wang YT</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CH%22">Lin CH</searchLink>; Department of Internal Medicine, Division of Chest Medicine, Changhua Christian Hospital, Changhua, Taiwan.; Institute of Genomics and Bioinformatics, National Chung Hsing University, Taichung, Taiwan.; Ph.D. Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+SF%22">Liu SF</searchLink>; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+MH%22">Cheng MH</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.; Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YF%22">Chen YF</searchLink>; Department of Internal Medicine, Yunlin Branch, National Taiwan University Hospital, Douliu, Taiwan.; Thoracic Medicine Center, Yunlin Branch, National Taiwan University Hospital, Douliu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+WC%22">Cheng WC</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+CK%22">Peng CK</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan.; Department of Medicine, Hualien Armed Forces General Hospital, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chan+MC%22">Chan MC</searchLink>; Department of Critical Care Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Post Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CY%22">Chen CY</searchLink>; Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jao+LY%22">Jao LY</searchLink>; School of Medicine, Tzu-Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CJ%22">Chen CJ</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+SP%22">Chen SP</searchLink>; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+YH%22">Tsai YH</searchLink>; Division of Pulmonary & Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.; Department of Pulmonary Medicine, Lees Clinic, Pingtung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+SL%22">Cheng SL</searchLink>; Division of Thoracic Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+HC%22">Lin HC</searchLink>; Department of Thoracic Medicine, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Respiratory Therapy, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chien+JY%22">Chien JY</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+HC%22">Wang HC</searchLink>; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.; Department of Respiratory Therapy, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; Department of Medicine, National Taiwan University Cancer Center, National Taiwan University College of Medicine, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%227701875%22">Lung</searchLink> [Lung] 2026 Apr 27; Vol. 204 (1). <i>Date of Electronic Publication: </i>2026 Apr 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7701875 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1750 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203412040%22">03412040 </searchLink><i>NLM ISO Abbreviation: </i>Lung <i>Subsets: </i>MEDLINE
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