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A cyclin D1-CDK4/6-E2F dependency represents an acquired vulnerability in cisplatin-resistant bladder cancer.

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Title: A cyclin D1-CDK4/6-E2F dependency represents an acquired vulnerability in cisplatin-resistant bladder cancer.
Authors: Hsieh TH; Center for Management and Development, Taipei Medical University, Taipei, 110301, Taiwan., Kuo HP; Center of Thoracic Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Department of Thoracic Medicine, Taipei Medical University Hospital, Taipei, 110301, Taiwan., Pan CH; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110301, Taiwan., Lin YC; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan., Lin BJ; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan., Chen MC; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110301, Taiwan. mcchen1250@tmu.edu.tw.; Traditional Herbal Medicine Research, Center of Taipei Medical University Hospital, Taipei, 110, Taiwan. mcchen1250@tmu.edu.tw., Chen CH; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. brianchc@tmu.edu.tw.; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, 116079, Taiwan. brianchc@tmu.edu.tw.
Source: Biology direct [Biol Direct] 2026 Apr 27; Vol. 21 (1). Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150 (Electronic) Linking ISSN: 17456150 NLM ISO Abbreviation: Biol Direct Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A cyclin D1-CDK4/6-E2F dependency represents an acquired vulnerability in cisplatin-resistant bladder cancer.
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  Data: <searchLink fieldCode="AU" term="%22Hsieh+TH%22">Hsieh TH</searchLink>; Center for Management and Development, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+HP%22">Kuo HP</searchLink>; Center of Thoracic Medicine, Taipei Medical University, Taipei, 110301, Taiwan.; Department of Thoracic Medicine, Taipei Medical University Hospital, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Pan+CH%22">Pan CH</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YC%22">Lin YC</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+BJ%22">Lin BJ</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+MC%22">Chen MC</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110301, Taiwan. mcchen1250@tmu.edu.tw.; Traditional Herbal Medicine Research, Center of Taipei Medical University Hospital, Taipei, 110, Taiwan. mcchen1250@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Chen+CH%22">Chen CH</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan. brianchc@tmu.edu.tw.; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, 116079, Taiwan. brianchc@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101258412%22">Biology direct</searchLink> [Biol Direct] 2026 Apr 27; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 Apr 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101258412 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6150 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456150%22">17456150 </searchLink><i>NLM ISO Abbreviation: </i>Biol Direct <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13062-026-00812-5
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      – TitleFull: A cyclin D1-CDK4/6-E2F dependency represents an acquired vulnerability in cisplatin-resistant bladder cancer.
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              Text: 2026 Apr 27
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