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SVO70 (Optimal Target Low-Density Lipoprotein Cholesterol Level for Small Vessel Occlusion Stroke): Rationale and Study Design.

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Title: SVO70 (Optimal Target Low-Density Lipoprotein Cholesterol Level for Small Vessel Occlusion Stroke): Rationale and Study Design.
Authors: Yang W; Department of Neurology Asan Medical Center, University of Ulsan College of Medicine Seoul Korea., Song TJ; Ewha Womans University Graduate Program in System Health Science and Engineering Department of Neurology Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine Seoul Korea., Koh SH; Department of Neurology Hanyang University Guri Hospital, Hanyang University College of Medicine Guri Korea., Jeong HS; Department of Neurology Chungnam National University Hospital, Chungnam National University College of Medicine Daejeon Korea., Sohn SI; Department of Neurology Keimyung University Dongsan Hospital, Keimyung University School of Medicine Daegu Korea., Kim YS; Department of Neurology Hanyang University Seoul Hospital, Hanyang University College of Medicine Seoul Korea., Kim BJ; Department of Neurology Seoul National University Bundang Hospital, Seoul National University College of Medicine Seongnam Korea., Jung JM; Department of Neurology Korea University Ansan Hospital, Korea University College of Medicine Ansan Korea., Jung KH; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea., Kim JM; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea., Jang H; Department of Neurology Asan Medical Center, University of Ulsan College of Medicine Seoul Korea., Lee EJ; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea., Chung M; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea., Kim S; Department of Neurology Kangwon National University Hospital, Kangwon National University College of Medicine Chuncheon Korea., Park HK; Department of Neurology Inha University Hospital, Inha University College of Medicine Incheon Korea., Yu S; Department of Neurology Korea University Anam Hospital, Korea University College of Medicine Seoul Korea., Cho YJ; Department of Neurology Inje University Ilsan Paik Hospital, Inje University College of Medicine Goyang Korea., Kim JT; Department of Neurology Chonnam National University Hospital, Chonnam National University Medical School Gwangju Korea., Kim Y; Department of Neurology Kangdong Sacred Heart Hospital, Hallym University College of Medicine Seoul Korea., Kim C; Department of Neurology Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine Chuncheon Korea., Kim HY; Department of Neurology Konkuk University Medical Center, Konkuk University School of Medicine Seoul Korea., Oh MS; Department of Neurology Hallym University Sacred Heart Hospital, Hallym University College of Medicine Anyang Korea., Kim DH; Department of Neurology Samsung Changwon Hospital, Sungkyunkwan University School of Medicine Changwon Korea., Lee YB; Department of Neurology Gil Medical Center, Gachon University College of Medicine Incheon Korea., Eun MY; Department of Neurology Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University Daegu Korea., Park HY; Department of Neurology Wonkwang University Hospital, Wonkwang University School of Medicine Iksan Korea., Kang K; Department of Neurology Nowon Eulji Medical Center, Eulji University School of Medicine Seoul Korea., Kwon HM; Department of Neurology Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine Seoul Korea., Cho HJ; Department of Neurology Pusan National University Hospital, Pusan National University School of Medicine Busan Korea., Kim JG; Department of Neurology Daejeon Eulji Medical Center, Eulji University School of Medicine Daejeon Korea., Choi JC; Department of Neurology Jeju National University Hospital, Jeju National University College of Medicine Jeju Korea., Yoo J; Department of Neurology Yongin Severance Hospital, Yonsei University College of Medicine Yongin Korea., Nam HS; Department of Neurology Severance Hospital, Yonsei University College of Medicine Seoul Korea., Ok T; Department of Neurology National Health Insurance Service Ilsan Hospital Ilsan Korea., Cho AH; Department of Neurology Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine Seoul Korea., Lee JY; Department of Neurology National Medical Center Seoul Korea., Shin JY; Department of Neurology Dongtan Sacred Heart Hospital, Hallym University College of Medicine Hwaseong Korea., Park JH; Department of Neurology Kyung Hee University Medical Center, Kyung Hee University College of Medicine Seoul Korea., Park KY; Department of Neurology Chung-Ang University Hospital, Chung-Ang University College of Medicine Seoul Korea., Shin DI; Department of Neurology Chungbuk National University Hospital, Chungbuk National University College of Medicine Cheongju Korea., Do Y; Department of Neurology Daegu Catholic University Medical Center, Daegu Catholic University School of Medicine Daegu Korea., Chang Y; Department of Neurology Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine Seoul Korea., Jung S; Department of Neurology Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine Changwon Korea., Jung YH; Department of Neurology Gangnam Severance Hospital, Yonsei University College of Medicine Seoul Korea., Seo WK; Department of Neurology Samsung Medical Center, Sungkyunkwan University School of Medicine Seoul Korea., Jeong SW; Department of Neurology Dongguk University Ilsan Hospital, Dongguk University College of Medicine Goyang Korea., Ha SY; Department of Neurology Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine Gwangmyeong Korea., An SJ; Department of Neurology International St. Mary's Hospital, Catholic Kwandong University College of Medicine Incheon Korea., Ahn SH; Department of Neurology Chosun University Hospital, Chosun University College of Medicine Gwangju Korea., Hwang YH; Department of Neurology Kyungpook National University Hospital, Kyungpook National University School of Medicine Daegu Korea., Lee SH; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 May 05; Vol. 15 (9), pp. e046824. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
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  Data: SVO70 (Optimal Target Low-Density Lipoprotein Cholesterol Level for Small Vessel Occlusion Stroke): Rationale and Study Design.
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  Data: <searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; Department of Neurology Asan Medical Center, University of Ulsan College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Song+TJ%22">Song TJ</searchLink>; Ewha Womans University Graduate Program in System Health Science and Engineering Department of Neurology Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Koh+SH%22">Koh SH</searchLink>; Department of Neurology Hanyang University Guri Hospital, Hanyang University College of Medicine Guri Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+HS%22">Jeong HS</searchLink>; Department of Neurology Chungnam National University Hospital, Chungnam National University College of Medicine Daejeon Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+SI%22">Sohn SI</searchLink>; Department of Neurology Keimyung University Dongsan Hospital, Keimyung University School of Medicine Daegu Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YS%22">Kim YS</searchLink>; Department of Neurology Hanyang University Seoul Hospital, Hanyang University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Kim+BJ%22">Kim BJ</searchLink>; Department of Neurology Seoul National University Bundang Hospital, Seoul National University College of Medicine Seongnam Korea.<br /><searchLink fieldCode="AU" term="%22Jung+JM%22">Jung JM</searchLink>; Department of Neurology Korea University Ansan Hospital, Korea University College of Medicine Ansan Korea.<br /><searchLink fieldCode="AU" term="%22Jung+KH%22">Jung KH</searchLink>; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JM%22">Kim JM</searchLink>; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Jang+H%22">Jang H</searchLink>; Department of Neurology Asan Medical Center, University of Ulsan College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Lee+EJ%22">Lee EJ</searchLink>; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Chung+M%22">Chung M</searchLink>; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Neurology Kangwon National University Hospital, Kangwon National University College of Medicine Chuncheon Korea.<br /><searchLink fieldCode="AU" term="%22Park+HK%22">Park HK</searchLink>; Department of Neurology Inha University Hospital, Inha University College of Medicine Incheon Korea.<br /><searchLink fieldCode="AU" term="%22Yu+S%22">Yu S</searchLink>; Department of Neurology Korea University Anam Hospital, Korea University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Cho+YJ%22">Cho YJ</searchLink>; Department of Neurology Inje University Ilsan Paik Hospital, Inje University College of Medicine Goyang Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JT%22">Kim JT</searchLink>; Department of Neurology Chonnam National University Hospital, Chonnam National University Medical School Gwangju Korea.<br /><searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; Department of Neurology Kangdong Sacred Heart Hospital, Hallym University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Kim+C%22">Kim C</searchLink>; Department of Neurology Hallym University Chuncheon Sacred Heart Hospital, Hallym University College of Medicine Chuncheon Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HY%22">Kim HY</searchLink>; Department of Neurology Konkuk University Medical Center, Konkuk University School of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Oh+MS%22">Oh MS</searchLink>; Department of Neurology Hallym University Sacred Heart Hospital, Hallym University College of Medicine Anyang Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DH%22">Kim DH</searchLink>; Department of Neurology Samsung Changwon Hospital, Sungkyunkwan University School of Medicine Changwon Korea.<br /><searchLink fieldCode="AU" term="%22Lee+YB%22">Lee YB</searchLink>; Department of Neurology Gil Medical Center, Gachon University College of Medicine Incheon Korea.<br /><searchLink fieldCode="AU" term="%22Eun+MY%22">Eun MY</searchLink>; Department of Neurology Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University Daegu Korea.<br /><searchLink fieldCode="AU" term="%22Park+HY%22">Park HY</searchLink>; Department of Neurology Wonkwang University Hospital, Wonkwang University School of Medicine Iksan Korea.<br /><searchLink fieldCode="AU" term="%22Kang+K%22">Kang K</searchLink>; Department of Neurology Nowon Eulji Medical Center, Eulji University School of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+HM%22">Kwon HM</searchLink>; Department of Neurology Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Cho+HJ%22">Cho HJ</searchLink>; Department of Neurology Pusan National University Hospital, Pusan National University School of Medicine Busan Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JG%22">Kim JG</searchLink>; Department of Neurology Daejeon Eulji Medical Center, Eulji University School of Medicine Daejeon Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JC%22">Choi JC</searchLink>; Department of Neurology Jeju National University Hospital, Jeju National University College of Medicine Jeju Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+J%22">Yoo J</searchLink>; Department of Neurology Yongin Severance Hospital, Yonsei University College of Medicine Yongin Korea.<br /><searchLink fieldCode="AU" term="%22Nam+HS%22">Nam HS</searchLink>; Department of Neurology Severance Hospital, Yonsei University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Ok+T%22">Ok T</searchLink>; Department of Neurology National Health Insurance Service Ilsan Hospital Ilsan Korea.<br /><searchLink fieldCode="AU" term="%22Cho+AH%22">Cho AH</searchLink>; Department of Neurology Yeouido St. Mary's Hospital, The Catholic University of Korea College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Neurology National Medical Center Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Shin+JY%22">Shin JY</searchLink>; Department of Neurology Dongtan Sacred Heart Hospital, Hallym University College of Medicine Hwaseong Korea.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; Department of Neurology Kyung Hee University Medical Center, Kyung Hee University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Park+KY%22">Park KY</searchLink>; Department of Neurology Chung-Ang University Hospital, Chung-Ang University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Shin+DI%22">Shin DI</searchLink>; Department of Neurology Chungbuk National University Hospital, Chungbuk National University College of Medicine Cheongju Korea.<br /><searchLink fieldCode="AU" term="%22Do+Y%22">Do Y</searchLink>; Department of Neurology Daegu Catholic University Medical Center, Daegu Catholic University School of Medicine Daegu Korea.<br /><searchLink fieldCode="AU" term="%22Chang+Y%22">Chang Y</searchLink>; Department of Neurology Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Jung+S%22">Jung S</searchLink>; Department of Neurology Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine Changwon Korea.<br /><searchLink fieldCode="AU" term="%22Jung+YH%22">Jung YH</searchLink>; Department of Neurology Gangnam Severance Hospital, Yonsei University College of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Seo+WK%22">Seo WK</searchLink>; Department of Neurology Samsung Medical Center, Sungkyunkwan University School of Medicine Seoul Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+SW%22">Jeong SW</searchLink>; Department of Neurology Dongguk University Ilsan Hospital, Dongguk University College of Medicine Goyang Korea.<br /><searchLink fieldCode="AU" term="%22Ha+SY%22">Ha SY</searchLink>; Department of Neurology Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine Gwangmyeong Korea.<br /><searchLink fieldCode="AU" term="%22An+SJ%22">An SJ</searchLink>; Department of Neurology International St. Mary's Hospital, Catholic Kwandong University College of Medicine Incheon Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+SH%22">Ahn SH</searchLink>; Department of Neurology Chosun University Hospital, Chosun University College of Medicine Gwangju Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+YH%22">Hwang YH</searchLink>; Department of Neurology Kyungpook National University Hospital, Kyungpook National University School of Medicine Daegu Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Department of Neurology Seoul National University Hospital, Seoul National University College of Medicine Seoul Korea.
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  Data: <searchLink fieldCode="JN" term="%22101580524%22">Journal of the American Heart Association</searchLink> [J Am Heart Assoc] 2026 May 05; Vol. 15 (9), pp. e046824. <i>Date of Electronic Publication: </i>2026 Apr 28.
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