Methoxyacetic acid exposure in rats induces N-butyrylglycinuria consistent with beta-oxidation impairment.
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| Title: | Methoxyacetic acid exposure in rats induces N-butyrylglycinuria consistent with beta-oxidation impairment. |
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| Authors: | Sala S; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia. Samuele.Sala@murdoch.edu.au., Kadyrov J; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia., Bernal A; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia., Castillo AM; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia.; Escuela de Ingeniería de Sistemas y Computación, Universidad del Valle, Cali, 76001, Colombia., Naraprasertkul P; Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Rd, Siriraj, Bangkok Noi, Bangkok, 10700, Thailand., Paesalasakul N; Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Rd, Siriraj, Bangkok Noi, Bangkok, 10700, Thailand., Bekanan P; Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Rd, Siriraj, Bangkok Noi, Bangkok, 10700, Thailand., Dhitsuwon I; Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wang Lang Rd, Siriraj, Bangkok Noi, Bangkok, 10700, Thailand., Kulthawatsiri T; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia.; The National Phenome Institute, Office of the President, Khon Kaen University, Khon Kaen, 40002, Thailand., Masuda R; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia., Sharma M; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia., Phetcharaburanin J; The National Phenome Institute, Office of the President, Khon Kaen University, Khon Kaen, 40002, Thailand.; Department of Systems Biosciences and Computational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand., Car BD; Formerly Bristol-Myers-Squibb Company, Princeton, NJ, USA., Contreras JIS; Faculty of Medicine, Institute of Global Health Innovation, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London, SW7 2NA, UK., Lindon JC; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, Burlington Danes Building, Du Cane Road, London, W12 0NN, UK., Wist J; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia.; Faculty of Medicine, Institute of Global Health Innovation, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London, SW7 2NA, UK.; Departamento de Química, Universidad del Valle, Cali, 76001, Colombia., Nicholson JK; Faculty of Medicine, Institute of Global Health Innovation, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London, SW7 2NA, UK., Holmes E; Centre for Computational and Systems Medicine, Health Futures Institute, Murdoch University, Harry Perkins Building, Perth, WA6150, Australia. Elaine.Holmes@murdoch.edu.au.; Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College, Burlington Danes Building, Du Cane Road, London, W12 0NN, UK. Elaine.Holmes@murdoch.edu.au. |
| Source: | Archives of toxicology [Arch Toxicol] 2026 Aug; Vol. 100 (8), pp. 3507-3518. Date of Electronic Publication: 2026 Apr 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
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