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Comparative analysis of distinct genomic landscapes in young-onset gBRCA1/2 breast cancer.

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Title: Comparative analysis of distinct genomic landscapes in young-onset gBRCA1/2 breast cancer.
Authors: Akamandisa MP; Division of Translational Medicine and Human Genetics and.; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Xia M; Division of Translational Medicine and Human Genetics and., Cheah W; University of Southampton, Southampton, United Kingdom., Wubbenhorst B; Division of Translational Medicine and Human Genetics and., D'Andrea KP; Division of Translational Medicine and Human Genetics and., Fan M; Division of Translational Medicine and Human Genetics and., Shilan JS; Division of Translational Medicine and Human Genetics and., Pueschl D; Division of Translational Medicine and Human Genetics and., Nayak A; Department of Pathology and Laboratory Medicine., McKenzie H; University of Southampton, Southampton, United Kingdom., Tapper W; University of Southampton, Southampton, United Kingdom., Copson ER; University of Southampton, Southampton, United Kingdom., Cutress RI; University of Southampton, Southampton, United Kingdom., Domchek SM; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Division of Hematology and Oncology, and.; Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Eccles DM; University of Southampton, Southampton, United Kingdom., Nathanson KL; Division of Translational Medicine and Human Genetics and.; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Source: JCI insight [JCI Insight] 2026 Apr 28; Vol. 11 (12). Date of Electronic Publication: 2026 Apr 28 (Print Publication: 2026).
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: <searchLink fieldCode="AU" term="%22Akamandisa+MP%22">Akamandisa MP</searchLink>; Division of Translational Medicine and Human Genetics and.; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Xia+M%22">Xia M</searchLink>; Division of Translational Medicine and Human Genetics and.<br /><searchLink fieldCode="AU" term="%22Cheah+W%22">Cheah W</searchLink>; University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wubbenhorst+B%22">Wubbenhorst B</searchLink>; Division of Translational Medicine and Human Genetics and.<br /><searchLink fieldCode="AU" term="%22D'Andrea+KP%22">D'Andrea KP</searchLink>; Division of Translational Medicine and Human Genetics and.<br /><searchLink fieldCode="AU" term="%22Fan+M%22">Fan M</searchLink>; Division of Translational Medicine and Human Genetics and.<br /><searchLink fieldCode="AU" term="%22Shilan+JS%22">Shilan JS</searchLink>; Division of Translational Medicine and Human Genetics and.<br /><searchLink fieldCode="AU" term="%22Pueschl+D%22">Pueschl D</searchLink>; Division of Translational Medicine and Human Genetics and.<br /><searchLink fieldCode="AU" term="%22Nayak+A%22">Nayak A</searchLink>; Department of Pathology and Laboratory Medicine.<br /><searchLink fieldCode="AU" term="%22McKenzie+H%22">McKenzie H</searchLink>; University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tapper+W%22">Tapper W</searchLink>; University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Copson+ER%22">Copson ER</searchLink>; University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cutress+RI%22">Cutress RI</searchLink>; University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Domchek+SM%22">Domchek SM</searchLink>; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Division of Hematology and Oncology, and.; Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Eccles+DM%22">Eccles DM</searchLink>; University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nathanson+KL%22">Nathanson KL</searchLink>; Division of Translational Medicine and Human Genetics and.; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Basser Center for BRCA, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2026 Apr 28; Vol. 11 (12). <i>Date of Electronic Publication: </i>2026 Apr 28 (<i>Print Publication: </i>2026).
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              Text: 2026 Apr 28
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