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Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses.

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Title: Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses.
Authors: Li SH; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Wang B; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Jo G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Mikelov A; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA., Atkinson RK; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Le Sage V; Center for Vaccine Research and Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA., Furey C; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Ort JT; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Ye N; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Gang S; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Shah R; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Santos JJS; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Röltgen K; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA., Joshi SA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA., Lee JY; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA., Pursell TA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA., Drapeau EM; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Han J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Callear AP; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Collman RG; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA., Monto AS; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Martin ET; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Lakdawala SS; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA., Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: wilson@scripps.edu., Boyd SD; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA. Electronic address: sboyd1@stanford.edu., Hensley SE; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address: hensley@pennmedicine.upenn.edu.
Source: Cell host & microbe [Cell Host Microbe] 2026 May 13; Vol. 34 (5), pp. 873-887.e11. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE
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  Data: Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses.
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  Data: <searchLink fieldCode="AU" term="%22Li+SH%22">Li SH</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Jo+G%22">Jo G</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Mikelov+A%22">Mikelov A</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Atkinson+RK%22">Atkinson RK</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Le+Sage+V%22">Le Sage V</searchLink>; Center for Vaccine Research and Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.<br /><searchLink fieldCode="AU" term="%22Furey+C%22">Furey C</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Ort+JT%22">Ort JT</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Ye+N%22">Ye N</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Gang+S%22">Gang S</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Shah+R%22">Shah R</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Santos+JJS%22">Santos JJS</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Röltgen+K%22">Röltgen K</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Joshi+SA%22">Joshi SA</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Pursell+TA%22">Pursell TA</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Drapeau+EM%22">Drapeau EM</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Callear+AP%22">Callear AP</searchLink>; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.<br /><searchLink fieldCode="AU" term="%22Collman+RG%22">Collman RG</searchLink>; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Monto+AS%22">Monto AS</searchLink>; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.<br /><searchLink fieldCode="AU" term="%22Martin+ET%22">Martin ET</searchLink>; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA.<br /><searchLink fieldCode="AU" term="%22Lakdawala+SS%22">Lakdawala SS</searchLink>; Department of Microbiology and Immunology, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+IA%22">Wilson IA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: wilson@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Boyd+SD%22">Boyd SD</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA. Electronic address: sboyd1@stanford.edu.<br /><searchLink fieldCode="AU" term="%22Hensley+SE%22">Hensley SE</searchLink>; Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address: hensley@pennmedicine.upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101302316%22">Cell host & microbe</searchLink> [Cell Host Microbe] 2026 May 13; Vol. 34 (5), pp. 873-887.e11. <i>Date of Electronic Publication: </i>2026 Apr 27.
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