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Evaluating Clinically Significant Prostate Cancer with Pathology-Registered Radiomics: A Multi-Reader Assessment Using Lesion Diameter-based Simplified Segmentations on MRI.

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Title: Evaluating Clinically Significant Prostate Cancer with Pathology-Registered Radiomics: A Multi-Reader Assessment Using Lesion Diameter-based Simplified Segmentations on MRI.
Authors: Esengur OT; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., Harmon SA; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., Gelikman DG; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., Yilmaz EC; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., Zhang H; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., Simon B; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., An JY; Department of Radiology, University of California San Diego, San Diego, CA (J.Y.A.)., Azamat S; Department of Radiology, Cam and Sakura City Hospital, Istanbul, Turkey (S.A.)., Law YM; Department of Radiology, Singapore General Hospital, Singapore (Y.M.L.)., Margolis DJA; Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.A.M.)., Marko J; Department of Radiology, Uniformed Services University, Bethesda, MD (J.M.)., Panebianco V; Department of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, Rome, Italy (V.P.)., Merino MJ; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD (M.J.M.)., Gurram S; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (S.G., P.A.P.)., Wood BJ; Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD (B.J.W., P.A.P.); Department of Radiology, Clinical Center, National Institutes of Health, Bethesda, MD (B.J.W.)., Lis R; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., Choyke PL; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.)., Pinto PA; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (S.G., P.A.P.); Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD (B.J.W., P.A.P.)., Turkbey B; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.). Electronic address: turkbeyi@mail.nih.gov.
Source: Academic radiology [Acad Radiol] 2026 Jul; Vol. 33 (7), pp. 2958-2973. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Association Of University Radiologists Country of Publication: United States NLM ID: 9440159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4046 (Electronic) Linking ISSN: 10766332 NLM ISO Abbreviation: Acad Radiol Subsets: MEDLINE
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  Data: Evaluating Clinically Significant Prostate Cancer with Pathology-Registered Radiomics: A Multi-Reader Assessment Using Lesion Diameter-based Simplified Segmentations on MRI.
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  Data: <searchLink fieldCode="AU" term="%22Esengur+OT%22">Esengur OT</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22Harmon+SA%22">Harmon SA</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22Gelikman+DG%22">Gelikman DG</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22Yilmaz+EC%22">Yilmaz EC</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22Simon+B%22">Simon B</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22An+JY%22">An JY</searchLink>; Department of Radiology, University of California San Diego, San Diego, CA (J.Y.A.).<br /><searchLink fieldCode="AU" term="%22Azamat+S%22">Azamat S</searchLink>; Department of Radiology, Cam and Sakura City Hospital, Istanbul, Turkey (S.A.).<br /><searchLink fieldCode="AU" term="%22Law+YM%22">Law YM</searchLink>; Department of Radiology, Singapore General Hospital, Singapore (Y.M.L.).<br /><searchLink fieldCode="AU" term="%22Margolis+DJA%22">Margolis DJA</searchLink>; Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.A.M.).<br /><searchLink fieldCode="AU" term="%22Marko+J%22">Marko J</searchLink>; Department of Radiology, Uniformed Services University, Bethesda, MD (J.M.).<br /><searchLink fieldCode="AU" term="%22Panebianco+V%22">Panebianco V</searchLink>; Department of Radiological Sciences, Oncology and Pathology, Sapienza University of Rome, Rome, Italy (V.P.).<br /><searchLink fieldCode="AU" term="%22Merino+MJ%22">Merino MJ</searchLink>; Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD (M.J.M.).<br /><searchLink fieldCode="AU" term="%22Gurram+S%22">Gurram S</searchLink>; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (S.G., P.A.P.).<br /><searchLink fieldCode="AU" term="%22Wood+BJ%22">Wood BJ</searchLink>; Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD (B.J.W., P.A.P.); Department of Radiology, Clinical Center, National Institutes of Health, Bethesda, MD (B.J.W.).<br /><searchLink fieldCode="AU" term="%22Lis+R%22">Lis R</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22Choyke+PL%22">Choyke PL</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.).<br /><searchLink fieldCode="AU" term="%22Pinto+PA%22">Pinto PA</searchLink>; Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (S.G., P.A.P.); Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD (B.J.W., P.A.P.).<br /><searchLink fieldCode="AU" term="%22Turkbey+B%22">Turkbey B</searchLink>; Molecular Imaging Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD (O.T.E., S.A.H., D.G.G., E.C.Y., H.Z., B.S., R.L., P.L.C., B.T.). Electronic address: turkbeyi@mail.nih.gov.
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  Data: <searchLink fieldCode="JN" term="%229440159%22">Academic radiology</searchLink> [Acad Radiol] 2026 Jul; Vol. 33 (7), pp. 2958-2973. <i>Date of Electronic Publication: </i>2026 Apr 27.
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