Integrating high-fidelity hiPSC-cardiomyocytes with AI-driven modeling for enhanced proarrhythmic risk assessment.

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Title: Integrating high-fidelity hiPSC-cardiomyocytes with AI-driven modeling for enhanced proarrhythmic risk assessment.
Authors: Kim SB; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea., Lee J; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea., An J; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea., Cho A; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea., Lee KH; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea., Choi H; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea., Han C; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea., Pramudito MA; Department of IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 39177, Republic of Korea., Lim KM; Department of Biomedical Engineering, Kumoh National Institute of Technology, Gumi, 39177, Republic of Korea. kmlim@kumoh.ac.kr.; Meta Heart Co., Ltd., Gumi, 39177, Republic of Korea. kmlim@kumoh.ac.kr., Woo DH; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea. dhwoo@nexel.co.kr.
Source: Archives of toxicology [Arch Toxicol] 2026 Aug; Vol. 100 (8), pp. 3553-3565. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrating high-fidelity hiPSC-cardiomyocytes with AI-driven modeling for enhanced proarrhythmic risk assessment.
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  Data: <searchLink fieldCode="AU" term="%22Kim+SB%22">Kim SB</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22An+J%22">An J</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+A%22">Cho A</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+C%22">Han C</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Pramudito+MA%22">Pramudito MA</searchLink>; Department of IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, 39177, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+KM%22">Lim KM</searchLink>; Department of Biomedical Engineering, Kumoh National Institute of Technology, Gumi, 39177, Republic of Korea. kmlim@kumoh.ac.kr.; Meta Heart Co., Ltd., Gumi, 39177, Republic of Korea. kmlim@kumoh.ac.kr.<br /><searchLink fieldCode="AU" term="%22Woo+DH%22">Woo DH</searchLink>; Department of Commercializing iPSC Technology, NEXEL Co., Ltd., 8th floor, 55 Magokdong-Ro, Gangseo-Gu, Seoul, 07802, Republic of Korea. dhwoo@nexel.co.kr.
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  Data: <searchLink fieldCode="JN" term="%220417615%22">Archives of toxicology</searchLink> [Arch Toxicol] 2026 Aug; Vol. 100 (8), pp. 3553-3565. <i>Date of Electronic Publication: </i>2026 Apr 28.
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        Value: 10.1007/s00204-026-04361-8
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        Text: English
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        StartPage: 3553
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            – D: 01
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              Text: 2026 Aug
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