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GPND-AI NULISA: A 15-Protein AI classifier for diagnosis and co-pathology profiling across neurodegenerative diseases.

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Title: GPND-AI NULISA: A 15-Protein AI classifier for diagnosis and co-pathology profiling across neurodegenerative diseases.
Authors: Xu Y; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Denkinger MN; Banner Sun Health Research Institute, Sun City, Arizona, USA., Liu M; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Gong K; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Chen Y; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Western D; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Timsina J; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Cheng Y; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Xie Y; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Mu R; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Budde J; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA., Beach TG; Banner Sun Health Research Institute, Sun City, Arizona, USA., Serrano GE; Banner Sun Health Research Institute, Sun City, Arizona, USA., Reiman EM; Banner Alzheimer's Institute, Phoenix, Arizona, USA., Singh A; Banner Sun Health Research Institute, Sun City, Arizona, USA., Alfradique-Dunham I; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Benzinger TLS; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA., Schindler SE; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurologic Disorders, Washington University, St. Louis, Missouri, USA., Morris JC; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA., Holtzman DM; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurologic Disorders, Washington University, St. Louis, Missouri, USA., Perlumtter JS; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neuroscience Programs in Occupational Therapy and Physical Therapy, Washington University School of Medicine, St. Louis, Missouri, USA., Snider BJ; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Campbell MC; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA., Kotzbauer PT; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA., Ashton NJ; Banner Sun Health Research Institute, Sun City, Arizona, USA.; Banner Alzheimer's Institute, Phoenix, Arizona, USA.; Department of Psychiatry and Neurochemistry Institute of Neuroscience & Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Västergötland, Sweden., Cruchaga C; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurologic Disorders, Washington University, St. Louis, Missouri, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 May; Vol. 22 (5), pp. e71420.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: GPND-AI NULISA: A 15-Protein AI classifier for diagnosis and co-pathology profiling across neurodegenerative diseases.
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  Data: <searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Denkinger+MN%22">Denkinger MN</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Gong+K%22">Gong K</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Western+D%22">Western D</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Timsina+J%22">Timsina J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+Y%22">Cheng Y</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Xie+Y%22">Xie Y</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Mu+R%22">Mu R</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Budde+J%22">Budde J</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Beach+TG%22">Beach TG</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Serrano+GE%22">Serrano GE</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Reiman+EM%22">Reiman EM</searchLink>; 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Hope Center for Neurologic Disorders, Washington University, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurologic Disorders, Washington University, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Perlumtter+JS%22">Perlumtter JS</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neuroscience Programs in Occupational Therapy and Physical Therapy, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Snider+BJ%22">Snider BJ</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Campbell+MC%22">Campbell MC</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Kotzbauer+PT%22">Kotzbauer PT</searchLink>; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Ashton+NJ%22">Ashton NJ</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, USA.; Banner Alzheimer's Institute, Phoenix, Arizona, USA.; Department of Psychiatry and Neurochemistry Institute of Neuroscience & Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Västergötland, Sweden.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.; NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, St. Louis, Missouri, USA.; Hope Center for Neurologic Disorders, Washington University, St. Louis, Missouri, USA.
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