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Structurally Engineered Carbonized Polycatechin for Targeting VEGF Signaling and Oxidative Stress in Corneal Neovascularization.

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Title: Structurally Engineered Carbonized Polycatechin for Targeting VEGF Signaling and Oxidative Stress in Corneal Neovascularization.
Authors: Lee WJ; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan., Tsai HW; Department of Biomedical Engineering and Center for Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan., Lee YJ; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan., Jian HJ; Department of Biomedical Engineering and Center for Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan., Chen CW; Institute of Analytical and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan., Lai JY; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; Department of Materials Engineering, Ming Chi University of Technology, New Taipei City, Taiwan.; Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan., Huang CC; Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.; Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan.; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan., Ko ML; Department of Ophthalmology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan., Lin HC; Department of Ophthalmology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan., Huang YF; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.; Institute of Analytical and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.
Source: Advanced healthcare materials [Adv Healthc Mater] 2026 Jun; Vol. 15 (21), pp. e05049. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101581613 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2192-2659 (Electronic) Linking ISSN: 21922640 NLM ISO Abbreviation: Adv Healthc Mater Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structurally Engineered Carbonized Polycatechin for Targeting VEGF Signaling and Oxidative Stress in Corneal Neovascularization.
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  Data: <searchLink fieldCode="AU" term="%22Lee+WJ%22">Lee WJ</searchLink>; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+HW%22">Tsai HW</searchLink>; Department of Biomedical Engineering and Center for Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+YJ%22">Lee YJ</searchLink>; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jian+HJ%22">Jian HJ</searchLink>; Department of Biomedical Engineering and Center for Biomedical Engineering, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CW%22">Chen CW</searchLink>; Institute of Analytical and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lai+JY%22">Lai JY</searchLink>; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.; Department of Materials Engineering, Ming Chi University of Technology, New Taipei City, Taiwan.; Research Center for Chinese Herbal Medicine, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CC%22">Huang CC</searchLink>; Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, Taiwan.; Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan.; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ko+ML%22">Ko ML</searchLink>; Department of Ophthalmology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+HC%22">Lin HC</searchLink>; Department of Ophthalmology, National Taiwan University Hospital, Hsin-Chu Branch, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YF%22">Huang YF</searchLink>; Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.; Institute of Analytical and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101581613%22">Advanced healthcare materials</searchLink> [Adv Healthc Mater] 2026 Jun; Vol. 15 (21), pp. e05049. <i>Date of Electronic Publication: </i>2026 Apr 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-VCH%22">Wiley-VCH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101581613 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2192-2659 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221922640%22">21922640 </searchLink><i>NLM ISO Abbreviation: </i>Adv Healthc Mater <i>Subsets: </i>MEDLINE
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        Value: 10.1002/adhm.202505049
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            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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