Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19.

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Title: Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19.
Authors: Hu R; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Valdivia A; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., White T; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Ju W; Emory University School of Medicine, Department of Pathology and Laboratory Medicine, Atlanta, Georgia, United States of America., Brockman ML; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Zhang Z; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Qu H; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Gafford G; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Joseph G; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Burton S; Emory National Primate Research Center, Emory University, Atlanta, Georgia, United States of America., Bassit L; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States of America., Charles TP; Emory National Primate Research Center, Emory University, Atlanta, Georgia, United States of America., Schinazi RF; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States of America., Levit RD; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Derdeyn CA; University of Washington, School of Medicine, Department of Laboratory Medicine and Pathology, Seattle, Washington, United States of America., Griendling KK; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Lassègue B; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America., Hernandes MS; Emory University School of Medicine, Department of Medicine, Division of Cardiology, Atlanta, Georgia, United States of America.
Source: PloS one [PLoS One] 2026 Apr 29; Vol. 21 (4), pp. e0348065. Date of Electronic Publication: 2026 Apr 29 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0348065