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Computational design of an ultrapotent deltacoronavirus miniprotein inhibitor.

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Title: Computational design of an ultrapotent deltacoronavirus miniprotein inhibitor.
Authors: Avery NG; Department of Biochemistry, University of Washington, Seattle, WA 98195., Yoshiyama CN; Department of Biochemistry, University of Washington, Seattle, WA 98195., Taylor AL; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112., Park YJ; Department of Biochemistry, University of Washington, Seattle, WA 98195.; HHMI, University of Washington, Seattle, WA 98195., Asarnow D; Department of Biochemistry, University of Washington, Seattle, WA 98195., Perruzza L; Humabs Biomed SA, a Subsidiary of Vir. Biotechnology, Bellinzona 6500, Switzerland., Brown JT; Department of Biochemistry, University of Washington, Seattle, WA 98195., Corti D; Humabs Biomed SA, a Subsidiary of Vir. Biotechnology, Bellinzona 6500, Switzerland., Benigni F; Humabs Biomed SA, a Subsidiary of Vir. Biotechnology, Bellinzona 6500, Switzerland., Starr TN; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112., Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195.; HHMI, University of Washington, Seattle, WA 98195.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 May 05; Vol. 123 (18), pp. e2533456123. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Computational design of an ultrapotent deltacoronavirus miniprotein inhibitor.
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  Data: <searchLink fieldCode="AU" term="%22Avery+NG%22">Avery NG</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195.<br /><searchLink fieldCode="AU" term="%22Yoshiyama+CN%22">Yoshiyama CN</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195.<br /><searchLink fieldCode="AU" term="%22Taylor+AL%22">Taylor AL</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112.<br /><searchLink fieldCode="AU" term="%22Park+YJ%22">Park YJ</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195.; HHMI, University of Washington, Seattle, WA 98195.<br /><searchLink fieldCode="AU" term="%22Asarnow+D%22">Asarnow D</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195.<br /><searchLink fieldCode="AU" term="%22Perruzza+L%22">Perruzza L</searchLink>; Humabs Biomed SA, a Subsidiary of Vir. Biotechnology, Bellinzona 6500, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brown+JT%22">Brown JT</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195.<br /><searchLink fieldCode="AU" term="%22Corti+D%22">Corti D</searchLink>; Humabs Biomed SA, a Subsidiary of Vir. Biotechnology, Bellinzona 6500, Switzerland.<br /><searchLink fieldCode="AU" term="%22Benigni+F%22">Benigni F</searchLink>; Humabs Biomed SA, a Subsidiary of Vir. Biotechnology, Bellinzona 6500, Switzerland.<br /><searchLink fieldCode="AU" term="%22Starr+TN%22">Starr TN</searchLink>; Department of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112.<br /><searchLink fieldCode="AU" term="%22Veesler+D%22">Veesler D</searchLink>; Department of Biochemistry, University of Washington, Seattle, WA 98195.; HHMI, University of Washington, Seattle, WA 98195.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 May 05; Vol. 123 (18), pp. e2533456123. <i>Date of Electronic Publication: </i>2026 Apr 29.
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              Text: 2026 May 05
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