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The DNA helicase HELQ promotes replication fork reversal in coordination with BRCA2- and FANCD2-mediated repair pathways.

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Title: The DNA helicase HELQ promotes replication fork reversal in coordination with BRCA2- and FANCD2-mediated repair pathways.
Authors: Dunbayev Y; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea., Chen YJ; Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan., Sassi L; Department of Oncology and Hematology-Oncology, University of Milan, Via Adamello 16, Milan 20139, Italy.; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Lee EA; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea., Ra JS; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea., Choi M; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea., Mukherjee A; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Boulevard, Austin, TX 78723, United States., Vasquez KM; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Boulevard, Austin, TX 78723, United States., Costanzo V; Department of Oncology and Hematology-Oncology, University of Milan, Via Adamello 16, Milan 20139, Italy.; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy., Chi P; Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan.; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan., Takata KI; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biomedical Engineering, College of Information-Bio Convergence Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Apr 23; Vol. 54 (8).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The DNA helicase HELQ promotes replication fork reversal in coordination with BRCA2- and FANCD2-mediated repair pathways.
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  Data: <searchLink fieldCode="AU" term="%22Dunbayev+Y%22">Dunbayev Y</searchLink>; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chen+YJ%22">Chen YJ</searchLink>; Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sassi+L%22">Sassi L</searchLink>; Department of Oncology and Hematology-Oncology, University of Milan, Via Adamello 16, Milan 20139, Italy.; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Lee+EA%22">Lee EA</searchLink>; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ra+JS%22">Ra JS</searchLink>; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+M%22">Choi M</searchLink>; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Mukherjee+A%22">Mukherjee A</searchLink>; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Boulevard, Austin, TX 78723, United States.<br /><searchLink fieldCode="AU" term="%22Vasquez+KM%22">Vasquez KM</searchLink>; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Dell Pediatric Research Institute, 1400 Barbara Jordan Boulevard, Austin, TX 78723, United States.<br /><searchLink fieldCode="AU" term="%22Costanzo+V%22">Costanzo V</searchLink>; Department of Oncology and Hematology-Oncology, University of Milan, Via Adamello 16, Milan 20139, Italy.; IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Chi+P%22">Chi P</searchLink>; Institute of Biochemical Sciences, National Taiwan University, Taipei 10617, Taiwan.; Institute of Biological Chemistry, Academia Sinica, Taipei 11529, Taiwan.<br /><searchLink fieldCode="AU" term="%22Takata+KI%22">Takata KI</searchLink>; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Republic of Korea.; Department of Biomedical Engineering, College of Information-Bio Convergence Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
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              Text: 2026 Apr 23
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