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MTHFD2: a promising metabolic checkpoint for diseases.

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Title: MTHFD2: a promising metabolic checkpoint for diseases.
Authors: Wang X; Hangzhou Geriatric Hospital, Department of Pharmacy, Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou, China., Ou R; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou, 310014, China.; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou, 310014, China., Xu Y; Hangzhou Geriatric Hospital, Department of Pharmacy, Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou, China., Zheng G; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou, 310014, China.; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou, 310014, China.; Otolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China., Xu H; Department of Clinical Laboratory, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China., Luo Y; Hangzhou Geriatric Hospital, Department of Pharmacy, Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou, China. luoying@hospital.westlake.edu.cn., Chen Y; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China. chenyunzhao@hmc.edu.cn., Ren X; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China. xxren8806@163.com.; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou, 310014, China. xxren8806@163.com.; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou, 310014, China. xxren8806@163.com.
Source: Journal of translational medicine [J Transl Med] 2026 Apr 29; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MTHFD2: a promising metabolic checkpoint for diseases.
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  Data: <searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Hangzhou Geriatric Hospital, Department of Pharmacy, Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Ou+R%22">Ou R</searchLink>; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou, 310014, China.; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou, 310014, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Hangzhou Geriatric Hospital, Department of Pharmacy, Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+G%22">Zheng G</searchLink>; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou, 310014, China.; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou, 310014, China.; Otolaryngology & Head and Neck Center, Cancer Center, Department of Head and Neck Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Department of Clinical Laboratory, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; Hangzhou Geriatric Hospital, Department of Pharmacy, Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou, China. luoying@hospital.westlake.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China. chenyunzhao@hmc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ren+X%22">Ren X</searchLink>; Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, 310014, China. xxren8806@163.com.; Zhejiang Provincial Clinical Research Center for Head & Neck Cancer, Hangzhou, 310014, China. xxren8806@163.com.; Zhejiang Key Laboratory of Precision Medicine Research on Head & Neck Cancer, Hangzhou, 310014, China. xxren8806@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Apr 29; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Apr 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-07764-4
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        Text: English
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              Text: 2026 Apr 29
              Type: published
              Y: 2026
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