Stress Accelerates Depressive-Like Behaviors through Increase of Notch2 Expression in N141I Mutation Presenilin-2 Transgenic Mice.

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Title: Stress Accelerates Depressive-Like Behaviors through Increase of Notch2 Expression in N141I Mutation Presenilin-2 Transgenic Mice.
Authors: Yoo SS; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Gu SM; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Nam KT; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Choi JS; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Lee YS; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Yeo IJ; Healthcare Convergence Educational Group for Infectious Disease Management, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic., Yu JE; Department of Pharmacy, College of Pharmacy, Mokpo National University, Muan 58554, Republic of Korea., Kim S; Stanley Brain Research Laboratory, Stanley Medical Research Institute, 9800 Medical Center Drive, Rockville, MD 20850, USA., Lee DW; National Institute of Food and Drug Safety Evaluation, Cheongju 28159, Republic of Korea., Ham HJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Chang JY; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Yun J; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Son DJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Han SB; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Hong JT; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.
Source: Biomolecules & therapeutics [Biomol Ther (Seoul)] 2026 May 01; Vol. 34 (3), pp. 544-555. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Korean Society of Applied Pharmacology Country of Publication: Korea (South) NLM ID: 101472832 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1976-9148 (Print) Linking ISSN: 19769148 NLM ISO Abbreviation: Biomol Ther (Seoul) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1976-9148
DOI:10.4062/biomolther.2025.246