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Stress Accelerates Depressive-Like Behaviors through Increase of Notch2 Expression in N141I Mutation Presenilin-2 Transgenic Mice.

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Title: Stress Accelerates Depressive-Like Behaviors through Increase of Notch2 Expression in N141I Mutation Presenilin-2 Transgenic Mice.
Authors: Yoo SS; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Gu SM; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Nam KT; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Choi JS; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Lee YS; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Yeo IJ; Healthcare Convergence Educational Group for Infectious Disease Management, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic., Yu JE; Department of Pharmacy, College of Pharmacy, Mokpo National University, Muan 58554, Republic of Korea., Kim S; Stanley Brain Research Laboratory, Stanley Medical Research Institute, 9800 Medical Center Drive, Rockville, MD 20850, USA., Lee DW; National Institute of Food and Drug Safety Evaluation, Cheongju 28159, Republic of Korea., Ham HJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Chang JY; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Yun J; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Son DJ; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Han SB; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea., Hong JT; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.
Source: Biomolecules & therapeutics [Biomol Ther (Seoul)] 2026 May 01; Vol. 34 (3), pp. 544-555. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Korean Society of Applied Pharmacology Country of Publication: Korea (South) NLM ID: 101472832 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1976-9148 (Print) Linking ISSN: 19769148 NLM ISO Abbreviation: Biomol Ther (Seoul) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Stress Accelerates Depressive-Like Behaviors through Increase of Notch2 Expression in N141I Mutation Presenilin-2 Transgenic Mice.
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  Data: <searchLink fieldCode="AU" term="%22Yoo+SS%22">Yoo SS</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Gu+SM%22">Gu SM</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nam+KT%22">Nam KT</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+JS%22">Choi JS</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+YS%22">Lee YS</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yeo+IJ%22">Yeo IJ</searchLink>; Healthcare Convergence Educational Group for Infectious Disease Management, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic.<br /><searchLink fieldCode="AU" term="%22Yu+JE%22">Yu JE</searchLink>; Department of Pharmacy, College of Pharmacy, Mokpo National University, Muan 58554, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Stanley Brain Research Laboratory, Stanley Medical Research Institute, 9800 Medical Center Drive, Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Lee+DW%22">Lee DW</searchLink>; National Institute of Food and Drug Safety Evaluation, Cheongju 28159, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ham+HJ%22">Ham HJ</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chang+JY%22">Chang JY</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yun+J%22">Yun J</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+DJ%22">Son DJ</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Han+SB%22">Han SB</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Hong+JT%22">Hong JT</searchLink>; College of Pharmacy and Medical Research Center, Chungbuk National University, Cheongju 28160, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101472832%22">Biomolecules & therapeutics</searchLink> [Biomol Ther (Seoul)] 2026 May 01; Vol. 34 (3), pp. 544-555. <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Korean+Society+of+Applied+Pharmacology%22">Korean Society of Applied Pharmacology </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>101472832 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1976-9148 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219769148%22">19769148 </searchLink><i>NLM ISO Abbreviation: </i>Biomol Ther (Seoul) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.4062/biomolther.2025.246
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              Text: 2026 May 01
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