Proarrhythmic Risk Assessment of Sildenafil under High-Dose Misuse Conditions Using the Comprehensive In Vitro Proarrhythmia Assay (CiPA).

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Title: Proarrhythmic Risk Assessment of Sildenafil under High-Dose Misuse Conditions Using the Comprehensive In Vitro Proarrhythmia Assay (CiPA).
Authors: Kim H; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea., Na TW; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea., Jung I; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea., Kang M; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea., Park S; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea., Kwon CH; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea., Jung K; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.
Source: Biomolecules & therapeutics [Biomol Ther (Seoul)] 2026 May 01; Vol. 34 (3), pp. 578-588. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Korean Society of Applied Pharmacology Country of Publication: Korea (South) NLM ID: 101472832 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1976-9148 (Print) Linking ISSN: 19769148 NLM ISO Abbreviation: Biomol Ther (Seoul) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Proarrhythmic Risk Assessment of Sildenafil under High-Dose Misuse Conditions Using the Comprehensive In Vitro Proarrhythmia Assay (CiPA).
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  Data: <searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink>; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Na+TW%22">Na TW</searchLink>; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+I%22">Jung I</searchLink>; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+M%22">Kang M</searchLink>; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+CH%22">Kwon CH</searchLink>; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+K%22">Jung K</searchLink>; Pharmacology and Narcotics Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju 28159, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101472832%22">Biomolecules & therapeutics</searchLink> [Biomol Ther (Seoul)] 2026 May 01; Vol. 34 (3), pp. 578-588. <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Korean+Society+of+Applied+Pharmacology%22">Korean Society of Applied Pharmacology </searchLink><i>Country of Publication: </i>Korea (South) <i>NLM ID: </i>101472832 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1976-9148 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219769148%22">19769148 </searchLink><i>NLM ISO Abbreviation: </i>Biomol Ther (Seoul) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.4062/biomolther.2025.097
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        Text: English
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      – TitleFull: Proarrhythmic Risk Assessment of Sildenafil under High-Dose Misuse Conditions Using the Comprehensive In Vitro Proarrhythmia Assay (CiPA).
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              Text: 2026 May 01
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