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Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice.

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Title: Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice.
Authors: Fan C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Cohen AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Dam KA; Gladstone Institutes, San Francisco, United States., Rorick AV; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Priso Fils AI; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Yang Z; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Gnanapragasam PNP; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Segovia LN; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Huey-Tubman KE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Moon WJ; Acuitas Therapeutics, Vancouver, Canada., Lin PJC; Acuitas Therapeutics, Vancouver, Canada., Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States., Hoffmann MAG; Gladstone Institutes, San Francisco, United States.; Department of Medicine, University of California, San Francisco, San Francisco, United States.
Source: ELife [Elife] 2026 Apr 30; Vol. 14. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice.
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  Data: <searchLink fieldCode="AU" term="%22Fan+C%22">Fan C</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Cohen+AA%22">Cohen AA</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Dam+KA%22">Dam KA</searchLink>; Gladstone Institutes, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Rorick+AV%22">Rorick AV</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Priso+Fils+AI%22">Priso Fils AI</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Gnanapragasam+PNP%22">Gnanapragasam PNP</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Segovia+LN%22">Segovia LN</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Huey-Tubman+KE%22">Huey-Tubman KE</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Moon+WJ%22">Moon WJ</searchLink>; Acuitas Therapeutics, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Lin+PJC%22">Lin PJC</searchLink>; Acuitas Therapeutics, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Bjorkman+PJ%22">Bjorkman PJ</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.<br /><searchLink fieldCode="AU" term="%22Hoffmann+MAG%22">Hoffmann MAG</searchLink>; Gladstone Institutes, San Francisco, United States.; Department of Medicine, University of California, San Francisco, San Francisco, United States.
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  Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2026 Apr 30; Vol. 14. <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22eLife+Sciences+Publications%2C+Ltd%22">eLife Sciences Publications, Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101579614 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-084X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222050084X%22">2050084X </searchLink><i>NLM ISO Abbreviation: </i>Elife <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42059889
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        Value: 10.7554/eLife.108959
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