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Local Salvage Therapy Alone for Local Recurrence of Prostate Cancer After Radiotherapy: A Systematic Review and Meta-Analysis.

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Title: Local Salvage Therapy Alone for Local Recurrence of Prostate Cancer After Radiotherapy: A Systematic Review and Meta-Analysis.
Authors: Miszczyk M; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Collegium Medicum, Faculty of Medicine, WSB University, Dąbrowa Górnicza, Poland., Mastroleo F; Department of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Kujawska A; Department of Urology and Oncological Urology, Poznan University of Medical Sciences, Poznań, Poland., Gurwin A; University Center of Excellence in Urology, Department of Minimally Invasive and Robotic Urology, Wroclaw Medical University, Wroclaw, Poland., Marvaso G; Department of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Kói T; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute of Mathematics, Department of Stochastics, Budapest University of Technology and Economics, Budapest, Hungary., Calleris G; Division of Urology, Department of Surgical Sciences, AOU Città della Salute e della Scienza di Torino, Torino School of Medicine, Turin, Italy., Rasing M; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Chin J; Department of Urology, Western University, London Health Sciences Centre, London, Ontario, Canada., Fuller D; Department of Radiation Oncology, UNIO Healthcare Partners, San Diego, California., Nathan A; Division of Surgery and Interventional Science, University College London, London, England.; Clinical Effectiveness Unit, Royal College of Surgeons of England, London, England., Peters M; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.; Radiotherapiegroep Deventer, Deventer, the Netherlands., van der Voort van Zyp J; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Jenjitranant P; Department of Urology, Western University, London Health Sciences Centre, London, Ontario, Canada., Hruby G; Northern Clinical School, University of Sydney, Sydney, New South Wales, Australia.; Department of Radiation Oncology, Royal North Shore Hospital, Sydney, New South Wales, Australia., Soeterik TFW; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands., Francolini G; Radiation Oncology Unit, Oncology Department, Azienda Ospedaliero Universitaria Careggi, Florence, Italy., Exterkate L; Department of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, the Netherlands., Overduin CG; Department of Medical Imaging, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., Marra G; Division of Urology, Department of Surgical Sciences, AOU Città della Salute e della Scienza di Torino, Torino School of Medicine, Turin, Italy., Gontero P; Division of Urology, Department of Surgical Sciences, AOU Città della Salute e della Scienza di Torino, Torino School of Medicine, Turin, Italy., Alfarhan AR; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Department of Urology, Prince Saud Bin Jalawi Hospital, Al Ahsa Health Cluster, Al Ahsa, Kingdom of Saudi Arabia., Rajwa P; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Division of Surgery and Interventional Sciences, University College London, London, England., Kishan AU; Department of Radiation Oncology, University of California, Los Angeles., Jereczek-Fossa BA; Department of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Shariat SF; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Corporate Authors: DEFER-PC Collaborators
Source: JAMA oncology [JAMA Oncol] 2026 Jun 01; Vol. 12 (6), pp. 637-647.
Publication Type: Systematic Review; Journal Article; Meta-Analysis
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101652861 Publication Model: Print Cited Medium: Internet ISSN: 2374-2445 (Electronic) Linking ISSN: 23742437 NLM ISO Abbreviation: JAMA Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Miszczyk+M%22">Miszczyk M</searchLink>; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Collegium Medicum, Faculty of Medicine, WSB University, Dąbrowa Górnicza, Poland.<br /><searchLink fieldCode="AU" term="%22Mastroleo+F%22">Mastroleo F</searchLink>; Department of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Kujawska+A%22">Kujawska A</searchLink>; Department of Urology and Oncological Urology, Poznan University of Medical Sciences, Poznań, Poland.<br /><searchLink fieldCode="AU" term="%22Gurwin+A%22">Gurwin A</searchLink>; University Center of Excellence in Urology, Department of Minimally Invasive and Robotic Urology, Wroclaw Medical University, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Marvaso+G%22">Marvaso G</searchLink>; Department of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Kói+T%22">Kói T</searchLink>; Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.; Institute of Mathematics, Department of Stochastics, Budapest University of Technology and Economics, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Calleris+G%22">Calleris G</searchLink>; Division of Urology, Department of Surgical Sciences, AOU Città della Salute e della Scienza di Torino, Torino School of Medicine, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Rasing+M%22">Rasing M</searchLink>; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Chin+J%22">Chin J</searchLink>; Department of Urology, Western University, London Health Sciences Centre, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Fuller+D%22">Fuller D</searchLink>; 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Northern Clinical School, University of Sydney, Sydney, New South Wales, Australia.; Department of Radiation Oncology, Royal North Shore Hospital, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Soeterik+TFW%22">Soeterik TFW</searchLink>; Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Francolini+G%22">Francolini G</searchLink>; Radiation Oncology Unit, Oncology Department, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Exterkate+L%22">Exterkate L</searchLink>; Department of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Overduin+CG%22">Overduin CG</searchLink>; Department of Medical Imaging, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Marra+G%22">Marra G</searchLink>; Division of Urology, Department of Surgical Sciences, AOU Città della Salute e della Scienza di Torino, Torino School of Medicine, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Gontero+P%22">Gontero P</searchLink>; Division of Urology, Department of Surgical Sciences, AOU Città della Salute e della Scienza di Torino, Torino School of Medicine, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Alfarhan+AR%22">Alfarhan AR</searchLink>; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Department of Urology, Prince Saud Bin Jalawi Hospital, Al Ahsa Health Cluster, Al Ahsa, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Rajwa+P%22">Rajwa P</searchLink>; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.; Division of Surgery and Interventional Sciences, University College London, London, England.<br /><searchLink fieldCode="AU" term="%22Kishan+AU%22">Kishan AU</searchLink>; Department of Radiation Oncology, University of California, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Jereczek-Fossa+BA%22">Jereczek-Fossa BA</searchLink>; Department of Radiation Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Shariat+SF%22">Shariat SF</searchLink>; Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
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