Depletion of renal cortical collecting duct-secreted PCSK9 in early proteinuria prevents sustained nephrotic syndrome-related hypercholesterolemia.

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Title: Depletion of renal cortical collecting duct-secreted PCSK9 in early proteinuria prevents sustained nephrotic syndrome-related hypercholesterolemia.
Authors: Molina-Jijon E; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States., Zavala-Guevara IP; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States., Gambut S; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States., Gomez-Sierra T; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States., Avila-Casado C; Department of Pathology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada., Macé C; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States., Clement LC; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.
Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2026 Jun 01; Vol. 330 (6), pp. F724-F734. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Depletion of renal cortical collecting duct-secreted PCSK9 in early proteinuria prevents sustained nephrotic syndrome-related hypercholesterolemia.
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  Data: <searchLink fieldCode="AU" term="%22Molina-Jijon+E%22">Molina-Jijon E</searchLink>; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Zavala-Guevara+IP%22">Zavala-Guevara IP</searchLink>; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Gambut+S%22">Gambut S</searchLink>; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Gomez-Sierra+T%22">Gomez-Sierra T</searchLink>; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Avila-Casado+C%22">Avila-Casado C</searchLink>; Department of Pathology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Macé+C%22">Macé C</searchLink>; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.<br /><searchLink fieldCode="AU" term="%22Clement+LC%22">Clement LC</searchLink>; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States.
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        Value: 10.1152/ajprenal.00350.2025
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      – TitleFull: Depletion of renal cortical collecting duct-secreted PCSK9 in early proteinuria prevents sustained nephrotic syndrome-related hypercholesterolemia.
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              Text: 2026 Jun 01
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