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Performance of a large language model on the reasoning tasks of a physician.

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Title: Performance of a large language model on the reasoning tasks of a physician.
Authors: Brodeur PG; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Buckley TA; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Kanjee Z; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Goh E; Stanford Division of Computational Medicine, Stanford University, Stanford, CA, USA.; Stanford Clinical Excellence Research Center, Stanford University, Stanford, CA, USA., Ling EB; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Jain P; Department of Internal Medicine, Cambridge Health Alliance, Cambridge, MA, USA., Cabral S; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA., Abdulnour RE; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Haimovich AD; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Freed JA; Department of Hematology-Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Olson A; Department of Hospital Medicine, University of Minnesota Medical School, Minneapolis, MN, USA., Morgan DJ; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.; Veterans Affairs Maryland Healthcare System, Baltimore, MD, USA., Hom J; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Gallo R; Center for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, CA USA.; Division of Hospital Medicine at Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, USA., McCoy LG; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Neurology, University of Alberta, Edmonton, AB, Canada., Mombini H; Technology and Innovation Group, Beth Israel Lahey Health, Boston, MA, USA., Lucas C; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Fotoohi M; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Gwiazdon M; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Restifo D; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Restrepo D; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Horvitz E; Microsoft, Redmond, WA, USA.; Stanford Institute for Human-Centered Artificial Intelligence, Stanford, CA, USA., Chen J; Stanford Division of Computational Medicine, Stanford University, Stanford, CA, USA.; Stanford Clinical Excellence Research Center, Stanford University, Stanford, CA, USA.; Division of Hospital Medicine, Department of Medicine, Stanford University, Stanford, CA, USA., Manrai AK; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Rodman A; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Source: Science (New York, N.Y.) [Science] 2026 Apr 30; Vol. 392 (6797), pp. 524-527. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Brodeur+PG%22">Brodeur PG</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Buckley+TA%22">Buckley TA</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kanjee+Z%22">Kanjee Z</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Goh+E%22">Goh E</searchLink>; Stanford Division of Computational Medicine, Stanford University, Stanford, CA, USA.; Stanford Clinical Excellence Research Center, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ling+EB%22">Ling EB</searchLink>; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jain+P%22">Jain P</searchLink>; Department of Internal Medicine, Cambridge Health Alliance, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cabral+S%22">Cabral S</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Abdulnour+RE%22">Abdulnour RE</searchLink>; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Haimovich+AD%22">Haimovich AD</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Freed+JA%22">Freed JA</searchLink>; Department of Hematology-Oncology, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Olson+A%22">Olson A</searchLink>; Department of Hospital Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Morgan+DJ%22">Morgan DJ</searchLink>; Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.; Veterans Affairs Maryland Healthcare System, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Hom+J%22">Hom J</searchLink>; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gallo+R%22">Gallo R</searchLink>; Center for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, CA USA.; Division of Hospital Medicine at Zuckerberg San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22McCoy+LG%22">McCoy LG</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Division of Neurology, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Mombini+H%22">Mombini H</searchLink>; Technology and Innovation Group, Beth Israel Lahey Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lucas+C%22">Lucas C</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fotoohi+M%22">Fotoohi M</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gwiazdon+M%22">Gwiazdon M</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Restifo+D%22">Restifo D</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Restrepo+D%22">Restrepo D</searchLink>; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Horvitz+E%22">Horvitz E</searchLink>; Microsoft, Redmond, WA, USA.; Stanford Institute for Human-Centered Artificial Intelligence, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Stanford Division of Computational Medicine, Stanford University, Stanford, CA, USA.; Stanford Clinical Excellence Research Center, Stanford University, Stanford, CA, USA.; Division of Hospital Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Manrai+AK%22">Manrai AK</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rodman+A%22">Rodman A</searchLink>; Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
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