CDK4/6 inhibitors plus endocrine therapy versus endocrine monotherapy in hormone receptor-positive, HER2-negative advanced breast cancer: a reconstructed individual patient data meta-analysis of phase 3 randomised controlled trials.

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Bibliographic Details
Title: CDK4/6 inhibitors plus endocrine therapy versus endocrine monotherapy in hormone receptor-positive, HER2-negative advanced breast cancer: a reconstructed individual patient data meta-analysis of phase 3 randomised controlled trials.
Authors: Beshr MS; Faculty of Medicine and Health Sciences, Sana'a University, Sana'a, Yemen., Fahaid A; Faculty of Medicine, University of Tripoli, Tripoli, Libya., Shembesh RH; Faculty of Medicine, Libyan International Medical University, Benghazi, Libya., Valachis A; Department of Oncology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden., Lambertini M; Department of Internal Medicine and Medical Specialties, School of Medicine, University of Genova, Genoa, Italy; Department of Medical Oncology, UO Clinical Di Oncologia Medica, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Cortesi L; Medical Oncology Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy; Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Alesawy AF; Clinical Microbiology and Immunology Department, Benha University, Qalubiya, Egypt., Abraheem A; Faculty of medicine, University of Al-azhar, Cairo, Egypt., Alsharedi M; Markey Cancer Center, UK HealthCare, University of Kentucky, KY, USA., Ali ME; Internal Medicine Department, Crestwood Medical Center, Huntsville, AL, USA., Elkhanany A; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA., Azim HA Jr; Cairo Cure Oncology Centre, Cairo, Egypt., Velikova G; Leeds Institute of Medical Research, University of Leeds, St James's University Hospital, Leeds, UK; Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Leeds, UK., Elhadi M; College of Medicine, Korea University, Seoul, South Korea. Electronic address: muhammed-elhadi@korea.ac.kr.
Source: The Lancet. Oncology [Lancet Oncol] 2026 May; Vol. 27 (5), pp. 592-603.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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