Clinical trial endpoints for metastases-directed therapy in oligometastatic cancer: a review and Delphi consensus on behalf of the EORTC-ESTRO OligoCare consortium.

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Title: Clinical trial endpoints for metastases-directed therapy in oligometastatic cancer: a review and Delphi consensus on behalf of the EORTC-ESTRO OligoCare consortium.
Authors: Widder J; Department of Radiation Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria. Electronic address: joachim.widder@muv.ac.at., Bol GM; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, Netherlands., Simek IM; Department of Radiation Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria., Ehret F; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Radiation Oncology, Berlin, Germany; German Cancer Consortium (DKTK), partner site Berlin, a partnership between DKFZ and Charité-Universitätsmedizin Berlin, Germany., Abdel-Aty H; The Royal Marsden Foundation Trust and Institute of Cancer Research, London, UK., Basic S; Rovinj, Croatia., Chuter D; ICPV (Independent Cancer Patients' Voice), London, UK; DiCE (Digestive Cancers Europe) Brussels, Belgium., Daly J; EGM Cancer Support, Galway, Ireland., Fairbrother P; ICPV (Independent Cancer Patients' Voice), London, UK., Zeqa D; Europa Donna Albania, Tirana, Albania; Europa Donna-The European Breast Cancer Coalition, Milan, Italy., Aboubakar Nana F; de Duve Institute, UCLouvain, Brussels, Belgium; Division of Pneumology, Cliniques Universitaires Saint-Luc, UCLouvain, Brussels, Belgium., Achard V; Radiotherapy Department, Institut Bergonié, Bordeaux, France; University of Geneva, Geneva, Switzerland., Corradini S; Department of Radiation Oncology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Correia D; Department of Radiation Oncology, Cantonal Hospital Aarau, Aarau, Switzerland; Department of Radiation Oncology, Inselspital, Bern, Switzerland; University Hospital, University of Bern, Switzerland., De Ruysscher D; Department of Radiation Oncology (Maastro Clinic), GROW Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, Netherlands., Dingemans AC; Department of Pulmonary Medicine, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Netherlands., Faivre-Finn C; The Christie NHS Foundation Trust & The University of Manchester, UK., Gillessen S; Oncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Guren MG; Department of Oncology, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Hendriks L; Department of Pulmonary Diseases, GROW Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, Netherlands., Kunz WG; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Lecouvet FE; Cliniques Universitaires Saint-Luc, UCLouvain, Brussels, Belgium; Department of Medical Imaging, Institut de Recherche Expérimentale et Clinique (IREC), Institut du Cancer Roi Albert II, Brussels, Belgium., Levy A; Université Paris-Saclay, Gustave Roussy, Department of Radiation Oncology, Villejuif, France., Lievens Y; Radiation Oncology Department, Ghent University Hospital, Ghent, Belgium; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., McDonald F; The Royal Marsden Foundation Trust and Institute of Cancer Research, London, UK., Meattini I; Department of Radiation Oncology (Maastro Clinic), GROW Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, Netherlands; Radiation Oncology, Breast Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy; Department of Experimental and Clinical Biomedical Sciences 'M Serio', University of Florence, Florence, Italy., Oppong F; European Organisation for Research and Treatment of Cancer (EORTC), Brussels, Belgium., Oprea-Lager D; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, Netherlands., Palma D; Department of Oncology, Western University, London, ON, Canada., Fredberg Persson G; Department of Oncology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Remon J; Department of Cancer Medicine, Villejuif, France., Vandemaele M; Radiation Oncology Department, Ghent University, Ghent, Belgium., van Laarhoven HWM; Amsterdam University Medical Center at the University of Amsterdam, Department of Medical Oncology, Amsterdam, Netherlands; Cancer Center Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, Netherlands., Verkooijen HM; Division of Imaging and Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands., Visani L; Radiation Oncology, Breast Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy., Zilli T; Faculty of Medicine, University of Geneva, Geneva, Switzerland; Department of Radiation Oncology, Oncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale, Bellinzona, Switzerland; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland., Ost P; Department of Human Structure and Repair, Ghent University, Ghent, Belgium; Department of Radiation Oncology, Iridium Network, Antwerp, Belgium., Guckenberger M; Department of Radiation Oncology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Source: The Lancet. Oncology [Lancet Oncol] 2026 May; Vol. 27 (5), pp. e238-e247.
Publication Type: Journal Article; Systematic Review; Consensus Statement; Review
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-5488
DOI:10.1016/S1470-2045(26)00075-6