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Exosomes derived from galangin preconditioned mesenchymal stem cells attenuate oxidative stress induced senescence and promote geriatric wound healing.

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Title: Exosomes derived from galangin preconditioned mesenchymal stem cells attenuate oxidative stress induced senescence and promote geriatric wound healing.
Authors: Wen SY; Department of Dermatology, Taipei City Hospital, Zhongxing Branch, Taipei, Taiwan, ROC.; Department of Cosmetic Applications and Management, Mackay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan, ROC.; Department of Health and Welfare, University of Taipei, Taipei, Taiwan, ROC., Ng SC; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC., Chiu YT; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC., Kao SW; Department of Orthopedic Surgery, Chung-Shan Medical University Hospital, Taichung, Taiwan, ROC.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC., Chen TJ; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC., Huang HY; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC., Huang CY; Center for Molecular Medicine in Traditional Chinese Medicine, E-Da Hospital, E-Da Healthcare Group, Kaohsiung, Taiwan.; School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Department of Biotechnology, Asia University, Taichung, Taiwan.; Graduate Institute of Biomedical Science, China Medical University, Taichung City, Taiwan.; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Kuo WW; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC. wwkuo@mail.cmu.edu.tw.; School of Pharmacy, China Medical University, Taichung, Taiwan, ROC. wwkuo@mail.cmu.edu.tw.
Source: Scientific reports [Sci Rep] 2026 Apr 30; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE; In Process
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  Data: Exosomes derived from galangin preconditioned mesenchymal stem cells attenuate oxidative stress induced senescence and promote geriatric wound healing.
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  Data: <searchLink fieldCode="AU" term="%22Wen+SY%22">Wen SY</searchLink>; Department of Dermatology, Taipei City Hospital, Zhongxing Branch, Taipei, Taiwan, ROC.; Department of Cosmetic Applications and Management, Mackay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan, ROC.; Department of Health and Welfare, University of Taipei, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Ng+SC%22">Ng SC</searchLink>; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chiu+YT%22">Chiu YT</searchLink>; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Kao+SW%22">Kao SW</searchLink>; Department of Orthopedic Surgery, Chung-Shan Medical University Hospital, Taichung, Taiwan, ROC.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+TJ%22">Chen TJ</searchLink>; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Huang+HY%22">Huang HY</searchLink>; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Center for Molecular Medicine in Traditional Chinese Medicine, E-Da Hospital, E-Da Healthcare Group, Kaohsiung, Taiwan.; School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.; Department of Biotechnology, Asia University, Taichung, Taiwan.; Graduate Institute of Biomedical Science, China Medical University, Taichung City, Taiwan.; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+WW%22">Kuo WW</searchLink>; Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan, ROC. wwkuo@mail.cmu.edu.tw.; School of Pharmacy, China Medical University, Taichung, Taiwan, ROC. wwkuo@mail.cmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Apr 30; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE; In Process
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42062410
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        Value: 10.1038/s41598-026-50218-6
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              Text: 2026 Apr 30
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