View in EDS

Deficient chaperone-mediated autophagy drives multiorgan fibrogenesis via SMAD2/4 stabilization to sustain TGFβ-SMAD signaling.

Saved in:
Bibliographic Details
Title: Deficient chaperone-mediated autophagy drives multiorgan fibrogenesis via SMAD2/4 stabilization to sustain TGFβ-SMAD signaling.
Authors: Jin JY; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Song YX; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Lu JB; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Nanhu Brain-computer Interface Institute, Hangzhou, 311100, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Li GQ; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Wang JQ; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Feng XJ; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Luo PH; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Yang B; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; School of Medicine, Hangzhou City University, Hangzhou, 310015, China., Xu ZF; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., Yan H; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China., He QJ; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. qiaojunhe@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, 311100, China. qiaojunhe@zju.edu.cn.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. qiaojunhe@zju.edu.cn.; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. qiaojunhe@zju.edu.cn., Yang XC; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yangxiaochun@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, 311100, China. yangxiaochun@zju.edu.cn.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yangxiaochun@zju.edu.cn.; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yangxiaochun@zju.edu.cn.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Apr 30. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42062474
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Deficient chaperone-mediated autophagy drives multiorgan fibrogenesis via SMAD2/4 stabilization to sustain TGFβ-SMAD signaling.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Jin+JY%22">Jin JY</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Song+YX%22">Song YX</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Lu+JB%22">Lu JB</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Nanhu Brain-computer Interface Institute, Hangzhou, 311100, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Li+GQ%22">Li GQ</searchLink>; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Wang+JQ%22">Wang JQ</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Feng+XJ%22">Feng XJ</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Luo+PH%22">Luo PH</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Yang+B%22">Yang B</searchLink>; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; School of Medicine, Hangzhou City University, Hangzhou, 310015, China.<br /><searchLink fieldCode="AU" term="%22Xu+ZF%22">Xu ZF</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22Yan+H%22">Yan H</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.<br /><searchLink fieldCode="AU" term="%22He+QJ%22">He QJ</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. qiaojunhe@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, 311100, China. qiaojunhe@zju.edu.cn.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. qiaojunhe@zju.edu.cn.; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. qiaojunhe@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yang+XC%22">Yang XC</searchLink>; Center for Drug Safety Evaluation and Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yangxiaochun@zju.edu.cn.; Nanhu Brain-computer Interface Institute, Hangzhou, 311100, China. yangxiaochun@zju.edu.cn.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yangxiaochun@zju.edu.cn.; Hangzhou Institute of Innovative Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China. yangxiaochun@zju.edu.cn.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22100956087%22">Acta pharmacologica Sinica</searchLink> [Acta Pharmacol Sin] 2026 Apr 30. <i>Date of Electronic Publication: </i>2026 Apr 30.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100956087 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-7254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216714083%22">16714083 </searchLink><i>NLM ISO Abbreviation: </i>Acta Pharmacol Sin <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42062474
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41401-026-01807-8
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Deficient chaperone-mediated autophagy drives multiorgan fibrogenesis via SMAD2/4 stabilization to sustain TGFβ-SMAD signaling.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Jin JY
      – PersonEntity:
          Name:
            NameFull: Song YX
      – PersonEntity:
          Name:
            NameFull: Lu JB
      – PersonEntity:
          Name:
            NameFull: Li GQ
      – PersonEntity:
          Name:
            NameFull: Wang JQ
      – PersonEntity:
          Name:
            NameFull: Feng XJ
      – PersonEntity:
          Name:
            NameFull: Luo PH
      – PersonEntity:
          Name:
            NameFull: Yang B
      – PersonEntity:
          Name:
            NameFull: Xu ZF
      – PersonEntity:
          Name:
            NameFull: Yan H
      – PersonEntity:
          Name:
            NameFull: He QJ
      – PersonEntity:
          Name:
            NameFull: Yang XC
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 30
              M: 04
              Text: 2026 Apr 30
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1745-7254
          Titles:
            – TitleFull: Acta pharmacologica Sinica
              Type: main
ResultId 1