STRAIGHT-IN Dual: a platform for dual single-copy integrations of DNA payloads and gene circuits into human induced pluripotent stem cells.
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| Title: | STRAIGHT-IN Dual: a platform for dual single-copy integrations of DNA payloads and gene circuits into human induced pluripotent stem cells. |
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| Authors: | Blanch-Asensio A; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, The Netherlands.; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Ploessl DS; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Johnson BB; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, The Netherlands., Cascione S; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands., Berndsen MRM; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, The Netherlands., Wang NB; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Orlova VV; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, The Netherlands., Alemany A; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, The Netherlands., Mummery CL; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, The Netherlands., Galloway KE; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. katiegal@mit.edu., Davis RP; Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands. r.p.davis@lumc.nl.; The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, Leiden University Medical Center, Leiden, The Netherlands. r.p.davis@lumc.nl. |
| Source: | Nature biomedical engineering [Nat Biomed Eng] 2026 Apr 30. Date of Electronic Publication: 2026 Apr 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-846X (Electronic) Linking ISSN: 2157846X NLM ISO Abbreviation: Nat Biomed Eng Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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