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Prior response to anti-VEGF agents predicts the efficacy of trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer.

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Title: Prior response to anti-VEGF agents predicts the efficacy of trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer.
Authors: Hirakawa M; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan. mhirakawa@sapmed.ac.jp., Sagawa T; Department of Gastroenterology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan., Okagawa Y; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan., Suzuki N; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan., Fujikawa K; Department of Gastroenterology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan., Takada K; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan.
Source: International journal of clinical oncology [Int J Clin Oncol] 2026 Jul; Vol. 31 (7), pp. 1267-1274. Date of Electronic Publication: 2026 Apr 30.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 9616295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-7772 (Electronic) Linking ISSN: 13419625 NLM ISO Abbreviation: Int J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Prior response to anti-VEGF agents predicts the efficacy of trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Hirakawa+M%22">Hirakawa M</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan. mhirakawa@sapmed.ac.jp.<br /><searchLink fieldCode="AU" term="%22Sagawa+T%22">Sagawa T</searchLink>; Department of Gastroenterology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Okagawa+Y%22">Okagawa Y</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+N%22">Suzuki N</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan.<br /><searchLink fieldCode="AU" term="%22Fujikawa+K%22">Fujikawa K</searchLink>; Department of Gastroenterology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Takada+K%22">Takada K</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan.
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  Data: <searchLink fieldCode="JN" term="%229616295%22">International journal of clinical oncology</searchLink> [Int J Clin Oncol] 2026 Jul; Vol. 31 (7), pp. 1267-1274. <i>Date of Electronic Publication: </i>2026 Apr 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Tokyo%22">Springer-Verlag Tokyo </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>9616295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1437-7772 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213419625%22">13419625 </searchLink><i>NLM ISO Abbreviation: </i>Int J Clin Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10147-026-03035-w
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        Text: English
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      – TitleFull: Prior response to anti-VEGF agents predicts the efficacy of trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer.
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              Text: 2026 Jul
              Type: published
              Y: 2026
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              Value: 31
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              Value: 7
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