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Exercise volume modulates cardiac protection in a type 2 diabetic rat model: differential effects of high- and low-volume moderate-intensity endurance exercise training on diabetic cardiomyopathy.

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Title: Exercise volume modulates cardiac protection in a type 2 diabetic rat model: differential effects of high- and low-volume moderate-intensity endurance exercise training on diabetic cardiomyopathy.
Authors: Simons R; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Bonilauri I; Cell Biology Area, Molecular Biology Department, University of León, León, 24007, Spain., Vastmans L; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Steegen L; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Heeren E; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Vandenboer V; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Verghote E; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., D'Haese S; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Claessen G; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium.; Department of Cardiology and Jessa & Science, Jessa Hospital, Stadsomvaart, Hasselt, 3500, Belgium., Lambrichts I; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Martín-Fernández B; Cell Biology Area, Molecular Biology Department, University of León, León, 24007, Spain., Volders PJ; BIOMED Research Institute, Department of Immunology & Infection, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Hansen D; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium.; Rehabilitation Research Centre (REVAL), Department of Rehabilitation Sciences, Hasselt University, Wetenschapspark 5-7, Diepenbeek, 3590, Belgium., Deluyker D; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium., Bito V; BIOMED Research Institute, Department of Cardio & Organsystems, Hasselt University, Agoralaan, Diepenbeek, 3590, Belgium. virginie.bito@uhasselt.be.
Source: Cardiovascular diabetology. Endocrinology reports [Cardiovasc Diabetol Endocrinol Rep] 2026 May 01; Vol. 12 (1). Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9918994893106676 Publication Model: Electronic Cited Medium: Internet ISSN: 3059-4057 (Electronic) Linking ISSN: 30594057 NLM ISO Abbreviation: Cardiovasc Diabetol Endocrinol Rep Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:3059-4057
DOI:10.1186/s40842-026-00288-2