Coordinated Engineering of Noncatalytic and Active-Site Regions in a Thermophilic D-Tagatose 4-Epimerase Enhances D-Tagatose Bioconversion from D-Fructose.

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Title: Coordinated Engineering of Noncatalytic and Active-Site Regions in a Thermophilic D-Tagatose 4-Epimerase Enhances D-Tagatose Bioconversion from D-Fructose.
Authors: Zhu Z; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China., Shen L; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China., Yu C; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China., Li Y; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China., Zhang B; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China., Hua L; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China., Leng Z; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China., Li Z; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.
Source: Journal of agricultural and food chemistry [J Agric Food Chem] 2026 May 13; Vol. 74 (18), pp. 14437-14446. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Coordinated Engineering of Noncatalytic and Active-Site Regions in a Thermophilic D-Tagatose 4-Epimerase Enhances D-Tagatose Bioconversion from D-Fructose.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.<br /><searchLink fieldCode="AU" term="%22Shen+L%22">Shen L</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.<br /><searchLink fieldCode="AU" term="%22Yu+C%22">Yu C</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.<br /><searchLink fieldCode="AU" term="%22Zhang+B%22">Zhang B</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.<br /><searchLink fieldCode="AU" term="%22Hua+L%22">Hua L</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.<br /><searchLink fieldCode="AU" term="%22Leng+Z%22">Leng Z</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China.
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  Data: <searchLink fieldCode="JN" term="%220374755%22">Journal of agricultural and food chemistry</searchLink> [J Agric Food Chem] 2026 May 13; Vol. 74 (18), pp. 14437-14446. <i>Date of Electronic Publication: </i>2026 May 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0374755 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-5118 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200218561%22">00218561 </searchLink><i>NLM ISO Abbreviation: </i>J Agric Food Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.jafc.6c00985
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        Text: English
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        StartPage: 14437
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      – TitleFull: Coordinated Engineering of Noncatalytic and Active-Site Regions in a Thermophilic D-Tagatose 4-Epimerase Enhances D-Tagatose Bioconversion from D-Fructose.
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              M: 05
              Text: 2026 May 13
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              Y: 2026
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