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Psychosocial implications, acceptability and ethics of screening for paediatric type 1 diabetes: a systematic review and mixed methods evidence synthesis.

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Title: Psychosocial implications, acceptability and ethics of screening for paediatric type 1 diabetes: a systematic review and mixed methods evidence synthesis.
Authors: Quinn LM; Institute of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK. l.quinn.1@bham.ac.uk., Stanley D; College of Medicine and Health, University of Birmingham, Birmingham, UK., Milano F; Department of Psychology, University of Milan-Bicocca, Milan, Italy., Perego G; School of Psychology, Vita Salute San Raffaele University, Milan, Italy.; Clinical and Health Psychology Unit, IRCCS San Raffaele Hospital, Milan, Italy., Randell MJ; Applied Health Directorate, Warwick Medical School, University of Warwick, Warwick, UK., Gatti F; School of Psychology, Vita Salute San Raffaele University, Milan, Italy., Catarinella A; Department of Psychology, University of Milan-Bicocca, Milan, Italy.; Clinical and Health Psychology Unit, IRCCS San Raffaele Hospital, Milan, Italy., Dettori LB; School of Psychology, Vita Salute San Raffaele University, Milan, Italy.; Clinical and Health Psychology Unit, IRCCS San Raffaele Hospital, Milan, Italy., Sheldon R; College of Medicine and Health, University of Birmingham, Birmingham, UK., Abid M; College of Medicine and Health, University of Birmingham, Birmingham, UK., Ziegler AG; Institute of Diabetes Research, Helmholtz Munich, and Forschergruppe Diabetes, Klinikum rechts der Isar, Technical University Munich, Munich, Germany., Bonifacio E; Center for Regenerative Therapies Dresden (CRTD), Faculty of Medicine, Technische Universität Dresden, Dresden, Germany., Mathieu C; Laboratory of Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven (KULEUVEN), Leuven, Belgium., Peakman M; Immunology & Inflammation Research Therapeutic Area, Sanofi, MA, USA., Dunne JL; Sanofi US, Bridgewater, NJ, USA., Hurtado Del Pozo C; Research Department, Breakthrough T1D, New York, NY, USA., Vercauteren J; Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Overbergh L; Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Bosi E; Diabetes Research Institute, IRCCS San Raffaele Hospital and Vita Salute San Raffaele University, Milan, Italy., Di Mattei VE; School of Psychology, Vita Salute San Raffaele University, Milan, Italy.; Clinical and Health Psychology Unit, IRCCS San Raffaele Hospital, Milan, Italy., Barnard K; Southern Health NHS Foundation Trust, Southampton, UK., Lange K; Department of Medical Psychology, Hannover Medical School, Hannover, Germany., Dias RP; Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Litchfield I; Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Greenfield SM; Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Boardman FK; Applied Health Directorate, Warwick Medical School, University of Warwick, Warwick, UK., Boiko O; Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Narendran P; Institute of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Corporate Authors: EDENT1FI consortium
Source: Diabetologia [Diabetologia] 2026 Jul; Vol. 69 (7), pp. 1759-1781. Date of Electronic Publication: 2026 May 01.
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE
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Department of Psychology, University of Milan-Bicocca, Milan, Italy.; Clinical and Health Psychology Unit, IRCCS San Raffaele Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dettori+LB%22">Dettori LB</searchLink>; School of Psychology, Vita Salute San Raffaele University, Milan, Italy.; Clinical and Health Psychology Unit, IRCCS San Raffaele Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sheldon+R%22">Sheldon R</searchLink>; College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Abid+M%22">Abid M</searchLink>; College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Ziegler+AG%22">Ziegler AG</searchLink>; Institute of Diabetes Research, Helmholtz Munich, and Forschergruppe Diabetes, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bonifacio+E%22">Bonifacio E</searchLink>; Center for Regenerative Therapies Dresden (CRTD), Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Mathieu+C%22">Mathieu C</searchLink>; Laboratory of Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven (KULEUVEN), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Peakman+M%22">Peakman M</searchLink>; Immunology & Inflammation Research Therapeutic Area, Sanofi, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dunne+JL%22">Dunne JL</searchLink>; Sanofi US, Bridgewater, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Hurtado+Del+Pozo+C%22">Hurtado Del Pozo C</searchLink>; Research Department, Breakthrough T1D, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Vercauteren+J%22">Vercauteren J</searchLink>; Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Overbergh+L%22">Overbergh L</searchLink>; Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Bosi+E%22">Bosi E</searchLink>; Diabetes Research Institute, IRCCS San Raffaele Hospital and Vita Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Mattei+VE%22">Di Mattei VE</searchLink>; School of Psychology, Vita Salute San Raffaele University, Milan, Italy.; Clinical and Health Psychology Unit, IRCCS San Raffaele Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Barnard+K%22">Barnard K</searchLink>; Southern Health NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Lange+K%22">Lange K</searchLink>; Department of Medical Psychology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Dias+RP%22">Dias RP</searchLink>; Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Litchfield+I%22">Litchfield I</searchLink>; Department of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Greenfield+SM%22">Greenfield SM</searchLink>; 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