Phase I Study of Telisotuzumab Adizutecan (Temab-A, ABBV-400), a Novel c-Met Antibody-Drug Conjugate, in Patients With Late-Line Colorectal Cancer and Advanced Solid Tumors.
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| Title: | Phase I Study of Telisotuzumab Adizutecan (Temab-A, ABBV-400), a Novel c-Met Antibody-Drug Conjugate, in Patients With Late-Line Colorectal Cancer and Advanced Solid Tumors. |
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| Authors: | Sharma MR; START Center for Cancer Research-Midwest, Grand Rapids, MI., Powderly J; Carolina BioOncology Institute, Huntersville, NC., Kuboki Y; Department of Experimental Therapeutics, National Cancer Center Hospital East, Kashiwa, Japan., Strickler JH; Duke University Medical Center, Durham, NC., Perets R; Rambam Medical Center and Technion-Israel Institute of Technology, Haifa, Israel., Cohen JE; Hadassah Hebrew University Medical Center, Jerusalem, Israel., Raimbourg J; Institut de Cancérologie de l'Ouest, Saint Herblain, France., Nakajima TE; Kyoto University Graduate School of Medicine, Kyoto-Shi, Japan., Yamamoto N; National Cancer Center Hospital, Tokyo, Japan., Cruz-Correa M; The University of Puerto Rico, Medical Sciences Campus, and Pan-American Center for Oncology Trials, San Juan, Puerto Rico., O'Neil B; Oncology, Community Health Network North Cancer Center, Indianapolis, IN., Ghiringhelli F; Department of Medical Oncology, Centre Georges François Leclerc, Dijon, France., Raghav K; The University of Texas MD Anderson Cancer Center, Houston, TX., Cecchini M; Yale University School of Medicine, New Haven, CT., Bar J; Jusidman Cancer Center, Sheba Medical Center, Ramat Gan, Israel.; The Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., Hunter Z; AbbVie Inc, North Chicago, IL., Burns M; AbbVie Inc, North Chicago, IL., Blaney M; AbbVie Inc, North Chicago, IL., Morrison-Thiele G; AbbVie Inc, North Chicago, IL., Aristide MN; AbbVie Inc, North Chicago, IL., Freise KJ; AbbVie Inc, North Chicago, IL., Li R; AbbVie Inc, North Chicago, IL., Li M; AbbVie Inc, North Chicago, IL., Vasilopoulos A; AbbVie Inc, North Chicago, IL., Biesdorf C; AbbVie Inc, North Chicago, IL., Sommerhalder D; NEXT Oncology, San Antonio, TX. |
| Source: | Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2026 Jul 10; Vol. 44 (20), pp. 1876-1888. Date of Electronic Publication: 2026 May 01. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Randomized Controlled Trial; Multicenter Study |
| Journal Info: | Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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