Clinically actionable genomic and transcriptomic landscape of advanced neuroendocrine neoplasms.
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| Title: | Clinically actionable genomic and transcriptomic landscape of advanced neuroendocrine neoplasms. |
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| Authors: | Kreutzfeldt S; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany., Apostolidis L; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany., Oleś M; Computational Oncology Group, Molecular Precision Oncology Program, NCT Heidelberg and DKFZ, Heidelberg, Germany., Krieghoff-Henning E; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; Division of Personalized Medical Oncology, DKFZ, Heidelberg, Germany; Department of Personalized Oncology, DKFZ-Hector Cancer Institute, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Department of Personalized Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Heilig CE; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany., Heining C; Department of Translational Medical Oncology, NCT, NCT/University Cancer Center Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology (TUD), and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, Dresden, Germany; DKTK, Partner Site Dresden, Dresden, Germany., Mock A; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; Institute of Pathology, Ludwig Maximilians University Munich, Munich, Germany; DKTK, Partner Site Munich, Munich, Germany., Teleanu MV; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany., Hutter B; Computational Oncology Group, Molecular Precision Oncology Program, NCT Heidelberg and DKFZ, Heidelberg, Germany., Gieldon L; Institute for Clinical Genetics, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, and Hereditary Cancer Syndrome Center Dresden, Dresden, Germany; European Reference Network for Genetic Tumour Risk Syndromes (ERN GENTURIS), Hereditary Cancer Syndrome Center Dresden, Dresden, Germany; Institute of Medical Genetics, Carl von Ossietzky University, Oldenburg, Germany., Klink B; Institute for Clinical Genetics, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, and Hereditary Cancer Syndrome Center Dresden, Dresden, Germany; Medizinisch Genetisches Zentrum, Munich, Germany; ERN GENTURIS, Nijmegen, the Netherlands., Beck K; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany., Richter D; Department of Translational Medical Oncology, NCT, NCT/University Cancer Center Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology (TUD), and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, Dresden, Germany., Baude-Müller A; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany., Reisinger E; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany., Hammer N; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany., Kamkar L; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany., Pfütze K; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany., Geörg C; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany., Lamping M; Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Berlin, Germany; DKTK, Partner Site Berlin, Berlin, Germany., Rieke DT; Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Berlin, Germany; DKTK, Partner Site Berlin, Berlin, Germany., Uhrig S; Computational Oncology Group, Molecular Precision Oncology Program, NCT Heidelberg and DKFZ, Heidelberg, Germany., Jann H; Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Department of Internal Medicine - Gastroenterology, Hematology and Oncology, Nephrology, DRK Kliniken Berlin Köpenick, Berlin, Germany., Pape UF; Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Berlin Institute of Health, Berlin, Germany., Allgäuer M; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Stenzinger A; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Winkler EC; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany., Wiedenmann B; Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Jäger D; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany., Brors B; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany; Division of Applied Bioinformatics, DKFZ, Heidelberg, Germany., Hübschmann D; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany; Computational Oncology Group, Molecular Precision Oncology Program, NCT Heidelberg and DKFZ, Heidelberg, Germany; Innovation and Service Unit for Bioinformatics and Precision Medicine, DKFZ, Heidelberg, Germany; Pattern Recognition and Digital Medicine Group, Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany., Schröck E; DKTK, Partner Site Dresden, Dresden, Germany; Institute for Clinical Genetics, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, and Hereditary Cancer Syndrome Center Dresden, Dresden, Germany; European Reference Network for Genetic Tumour Risk Syndromes (ERN GENTURIS), Hereditary Cancer Syndrome Center Dresden, Dresden, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany., Keilholz U; Charité Comprehensive Cancer Center, Charité - Universitätsmedizin Berlin, Berlin, Germany; DKTK, Partner Site Berlin, Berlin, Germany., Pavel M; Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Department of Medicine 1, Division of Endocrinology, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany., Horak P; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany., Glimm H; Department of Translational Medical Oncology, NCT, NCT/University Cancer Center Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology (TUD), and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany; Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD, Dresden, Germany; DKTK, Partner Site Dresden, Dresden, Germany; Translational Functional Cancer Genomics, DKFZ, Heidelberg, Germany., Fröhling S; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany; Institute of Human Genetics, Heidelberg University, Heidelberg, Germany. Electronic address: stefan.froehling@nct-heidelberg.de. |
| Source: | Med (New York, N.Y.) [Med] 2026 Jun 12; Vol. 7 (6), pp. 101130. Date of Electronic Publication: 2026 Apr 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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